(Q33825216)

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Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences

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scholarly article

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1 November 2019

Efficient processing of the immunodominant, HLA-A*0201-restricted human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitope despite multiple variations in the epitope flanking sequences (English)

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1 November 2019

Christian Brander

1

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1 November 2019

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O O Yang

2

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1 November 2019

N G Jones

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1 November 2019

Y Lee

4

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1 November 2019

P Goulder

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1 November 2019

R P Johnson

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1 November 2019

A Trocha

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1 November 2019

D Colbert

8

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1 November 2019

C Hay

9

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1 November 2019

S Buchbinder

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1 November 2019

C C Bergmann

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1 November 2019

H J Zweerink

12

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1 November 2019

S Wolinsky

13

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1 November 2019

W A Blattner

14

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1 November 2019

S A Kalams

15

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1 November 2019

B D Walker

16

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1 November 2019

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1 December 1999

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1 November 2019

Journal of Virology

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1 November 2019

73

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1 November 2019

10191-10198

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1 November 2019

12

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1 November 2019

Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Lack of viral escape and defective in vivo activation of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes in rapidly progressive infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Viral immune evasion due to persistence of activated T cells without effector function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Lack of strong immune selection pressure by the immunodominant, HLA-A*0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

T cells chronically infected with HIV do not contain sufficient Nef to promote CD4 downmodulation in the absence of envelope-mediated effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Murine transporter associated with antigen presentation (TAP) preferences influence class I-restricted T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Multi-epitope DNA vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Absence of functional relevance of human transporter associated with antigen processing polymorphism for peptide selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Nonreplicating recombinant vaccinia virus encoding human B-7 molecules elicits effective costimulation of naive and memory CD4+ T lymphocytes in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Identification of type-specific cytotoxic T lymphocyte responses to homologous viral proteins in laboratory workers accidentally infected with HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Flanking residues alter antigenicity and immunogenicity of multi-unit CTL epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

How selective is the transporter associated with antigen processing?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Selectivity of MHC-encoded peptide transporters from human, mouse and rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Antagonists or altruists: do viral mutants modulate T-cell responses?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Differential effects of flanking residues on presentation of epitopes from chimeric peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

The peptide-binding motif for the human transporter associated with antigen processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Recognition of influenza A virus nucleoprotein by human cytotoxic T lymphocytes

1 reference

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4 July 2018

Risk of human immunodeficiency virus (HIV-1) infection among laboratory workers

1 reference

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4 July 2018

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Course of HIV-I infection in a cohort of homosexual and bisexual men: an 11 year follow up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

4 July 2018

Cytotoxic T lymphocytes do not appear to select for mutations in an immunodominant epitope of simian immunodeficiency virus gag

1 reference

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4 July 2018

T cell responses and viral escape

1 reference

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29 October 2018

CD8+ cells in human immunodeficiency virus type I pathogenesis: cytolytic and noncytolytic inhibition of viral replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

29 October 2018

Overexpression of the HIV-1 gag-pol polyprotein results in intracellular activation of HIV-1 protease and inhibition of assembly and budding of virus-like particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

29 October 2018

Presentation of endogenous peptides to MHC class I-restricted cytotoxic T lymphocytes in transport deletion mutant T2 cells

1 reference

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29 October 2018

The cleavage preference of the proteasome governs the yield of antigenic peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113072

29 October 2018

Recombinant polyepitope vaccines for the delivery of multiple CD8 cytotoxic T cell epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-specific cytotoxic T lymphocytes in seropositive individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 reverse transcriptase is a target for cytotoxic T lymphocytes in infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. Fine specificity of the gag-specific response defined by using unstimulated peripheral blood mononuclear cells and cloned effector cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/10559335

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.73.12.10191-10198.1999

0 references

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Europe PubMed Central

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1 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10559335%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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