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Using photolabile ligands in drug discovery and development.
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Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
review article
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Europe PubMed Central
title
Using photolabile ligands in drug discovery and development
(English)
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stated in
Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
drug discovery
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author
György Dormán
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
Prestwich GD
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 February 2000
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Europe PubMed Central
PubMed publication ID
10652511
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Trends in Biotechnology
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Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
18
1 reference
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Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
64-77
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Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Photoaffinity labels as pharmacological tools
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7 January 2021
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New photolabeling and crosslinking methods
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Crossref
reference URL
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Benzophenone photoprobes for phosphoinositides, peptides and drugs
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Crossref
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7 January 2021
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Spatially Addressable Combinatorial Libraries
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7 January 2021
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Controlling cell chemistry with caged compounds
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7 January 2021
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Benzophenone photophores in biochemistry.
1 reference
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7 January 2021
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Proteomics: a major new technology for the drug discovery process
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Crossref
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7 January 2021
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Comparison of the photochemical behavior of four different photoactivatable probes
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Crossref
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7 January 2021
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Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly [...]
1 reference
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Crossref
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7 January 2021
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Characterization of AT4 receptor from bovine aortic endothelium with photosensitive analogues of angiotensin IV
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
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Identification of a ligand binding site in the human neutrophil formyl peptide receptor using a site-specific fluorescent photoaffinity label and mass spectrometry.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
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Structurally similar small molecule photoaffinity CCK-A agonists and antagonists as novel tools for directly probing 7TM receptors-ligand interactions
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
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Synthesis and characterization of a photoactivatable analog of corticotropin-releasing factor for specific receptor labeling
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Crossref
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7 January 2021
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Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies
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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
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Photoaffinity analogue for the anti-inflammatory drug alpha-trinositol: synthesis and identification of putative molecular targets
1 reference
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Crossref
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7 January 2021
based on heuristic
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Photoaffinity analog of the semisynthetic echinocandin LY303366: identification of echinocandin targets in Candida albicans
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
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Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase
1 reference
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Crossref
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7 January 2021
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Photoaffinity labeling of oxidosqualene cyclase and squalene cyclase by a benzophenone-containing inhibitor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The binding site for an inhibitor of squalene:hopene cyclase determined using photoaffinity labeling and molecular modeling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
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Photoaffinity labeling of rat steroid 5 alpha-reductase (isozyme-1) by a benzophenone derivative of a 4-methyl-4-azasteroid
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
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Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inositol 1,4,5-trisphosphate receptors: labeling the inositol 1,4,5-trisphosphate binding site with photoaffinity ligands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Probing the phosphoinositide 4,5-bisphosphate binding site of human profilin I
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Probing the phosphoinositide binding site of the clathrin assembly protein AP-2 with photoaffinity labels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Specific interaction of Golgi coatomer protein alpha-COP with phosphatidylinositol 3,4,5-trisphosphate
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Photoaffinity substrates for P-glycoprotein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
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Interaction of cytostatics and chemosensitizers with the dexniguldipine binding site on P-glycoprotein
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Identification of the domains of photoincorporation of the 3'- and 7-benzophenone analogues of taxol in the carboxyl-terminal half of murine mdr1b P-glycoprotein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
A New Paclitaxel Photoaffinity Analog with a 3-(4-Benzoylphenyl)propanoyl Probe for Characterization of Drug-Binding Sites on Tubulin and P-Glycoprotein
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Photoimmobilization of sulfated hyaluronic acid for antithrombogenicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Micropatterning gradients and controlling surface densities of photoactivatable biomolecules on self-assembled monolayers of oligo(ethylene glycol) alkanethiolates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and characterization of a photoactivatable glycoaryldiazirine for surface glycoengineering
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of microscale gradients of protein using heterobifunctional photolinkers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and photochemical properties of a kainate precursor and activation of kainate and AMPA receptor channels on a microsecond time scale
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
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inferred from DOI database lookup
N-Nmoc-L-glutamate, a new caged glutamate with high chemical stability and low pre-photolysis activity
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Brominated 7-hydroxycoumarin-4-ylmethyls: photolabile protecting groups with biologically useful cross-sections for two photon photolysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane-permeant esters of inositol polyphosphates, chemical syntheses and biological applications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a ganglioside recognition domain of tetanus toxin using a novel ganglioside photoaffinity ligand.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthesis, photoreactivity and cytotoxic activity of caged compounds of L-leucyl-L-leucine methyl ester, an apoptosis inducer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Light-activated proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caged cysteine and thiophosphoryl peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A photoactivated prodrug
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitrobenzyl-Based Photosensitive Phosphoramide Mustards: Synthesis and Photochemical Properties of Potential Prodrugs for Cancer Therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of pH on aggregation and photoproperties of n-(2-hydroxypropyl)methacrylamide copolymer-meso-chlorin e6 conjugates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preparation and photoactivation of caged fluorophores and caged proteins using a new class of heterobifunctional, photocleavable cross-linking reagents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A general method for the spatially defined immobilization of biomolecules on glass surfaces using "caged" biotin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Six new photolabile linkers for solid-phase synthesis. 1. Methods of preparation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901402-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-7799(99)01402-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
10652511
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10652511
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10652511%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
ResearchGate publication ID
12661273
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