(Q33828926)

29 July 2017

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title

TGF-beta receptors and DNA repair genes, coupled targets in a pathway of human colon carcinogenesis (English)

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29 July 2017

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S Markowitz

1

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29 July 2017

language of work or name

English

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publication date

1 February 2000

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Biochimica et Biophysica Acta

29 July 2017

published in

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29 July 2017

volume

1470

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29 July 2017

issue

1

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29 July 2017

page(s)

M13-20

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Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.

29 July 2017

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GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

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Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

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Hypermutability and mismatch repair deficiency in RER+ tumor cells

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Mutator phenotypes in human colorectal carcinoma cell lines

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Clues to the pathogenesis of familial colorectal cancer

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Microsatellite instability in cancer of the proximal colon

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

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Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

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Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

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7 January 2021

The transforming growth factor-beta family

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7 January 2021

The TGF-beta family and its composite receptors

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7 January 2021

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1

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Transforming growth factor-beta 1 (TGF beta 1) enhances apoptosis in human papillomavirus type 16-immortalized human ectocervical epithelial cells

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7 January 2021

A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor gene

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7 January 2021

TGF-beta expression in the human colon: differential immunostaining along crypt epithelium

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7 January 2021

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

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7 January 2021

Ultrastructure of cell loss in intestinal mucosa

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7 January 2021

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

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7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

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7 January 2021

Mechanism of activation of the TGF-beta receptor

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7 January 2021

A transforming growth factor beta type I receptor that signals to activate gene expression

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7 January 2021

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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7 January 2021

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7 January 2021

Tumor suppressing pathways

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7 January 2021

Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases

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7 January 2021

Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest

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7 January 2021

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

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7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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7 January 2021

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

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7 January 2021

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

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7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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7 January 2021

TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights

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7 January 2021

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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7 January 2021

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

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7 January 2021

Mad-related genes in the human

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7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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7 January 2021

Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells

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7 January 2021

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Identifiers

DOI

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29 July 2017

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