(Q33831073)

English

Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

29 July 2017

Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma (English)

1 reference

Europe PubMed Central

29 July 2017

1 reference

based on heuristic

inferred from title

monoclonal antibody

1 reference

based on heuristic

inferred from title

author name string

Joseph M Parker

1

1 reference

Europe PubMed Central

29 July 2017

Chad K Oh

2

1 reference

Europe PubMed Central

29 July 2017

Craig LaForce

3

1 reference

Europe PubMed Central

29 July 2017

S David Miller

4

1 reference

Europe PubMed Central

29 July 2017

David S Pearlman

5

1 reference

Europe PubMed Central

29 July 2017

Chenxiong Le

6

1 reference

Europe PubMed Central

29 July 2017

Gabriel J Robbie

7

1 reference

Europe PubMed Central

29 July 2017

Wendy I White

8

1 reference

Europe PubMed Central

29 July 2017

Barbara White

9

1 reference

Europe PubMed Central

29 July 2017

Nestor A Molfino

10

1 reference

Europe PubMed Central

29 July 2017

MEDI-528 Clinical Trials Group

11

1 reference

Europe PubMed Central

29 July 2017

publication date

28 February 2011

1 reference

Europe PubMed Central

29 July 2017

BMC Pulmonary Medicine

1 reference

Europe PubMed Central

29 July 2017

11

1 reference

Europe PubMed Central

29 July 2017

14

1 reference

Europe PubMed Central

29 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2466-11-14

0 references

Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

American Academy of Allergy, Asthma & Immunology Work Group report: exercise-induced asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

The asthma epidemic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Indirect bronchial hyper-responsiveness: the coming of age of a specific group of bronchial challenges.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

IL-9 in allergic inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

IL-9 expression by human eosinophils: regulation by IL-1beta and TNF-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Interleukin 9: a candidate gene for asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Identification and partial characterization of an exercise-induced neutrophil chemotactic factor in bronchial asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058114

28 July 2018

Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

IL-9 increases the expression of several cytokines in activated mast cells, while the IL-9-induced IL-9 production is inhibited in mast cells of histamine-free transgenic mice

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchiolitis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Anti-interleukin-9 antibody treatment inhibits airway inflammation and hyperreactivity in mouse asthma model.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Effect of anti-mIL-9 antibody on the development of pulmonary inflammation and airway hyperresponsiveness in allergic mice

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Elevated expression of interleukin-9 mRNA in the bronchial mucosa of atopic asthmatics and allergen-induced cutaneous late-phase reaction: relationships to eosinophils, mast cells and T lymphocytes.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

A calcium-activated chloride channel (HCLCA1) is strongly related to IL-9 expression and mucus production in bronchial epithelium of patients with asthma

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Two first-in-human, open-label, phase I dose-escalation safety trials of MEDI-528, a monoclonal antibody against interleukin-9, in healthy adult volunteers.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Validation of a standardized version of the Asthma Quality of Life Questionnaire.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Standardisation of spirometry

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Profibrotic Effect of IL-9 Overexpression in a Model of Airway Remodeling

1 reference

https://api.crossref.org/works/10.1186%2F1471-2466-11-14

21 January 2018

Guidelines for methacholine and exercise challenge testing-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999

1 reference

https://pubmed.ncbi.nlm.nih.gov/21356110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine bone marrow-derived mast cells as potent producers of IL-9: costimulatory function of IL-10 and kit ligand in the presence of IL-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21356110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21356110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-9 and its receptor in allergic and nonallergic lung disease: increased expression in asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21356110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2466-11-14

1 reference

Europe PubMed Central

29 July 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33831073&oldid=1647960781"