(Q33831443)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Identification of pyruvate kinase in methicillin-resistant Staphylococcus aureus as a novel antimicrobial drug target (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

methicillin-resistant Staphylococcus aureus

23 January 2020

main subject

0 references

Staphylococcus aureus

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Roya Zoraghi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Raymond H See

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Peter Axerio-Cilies

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Nag S Kumar

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Huansheng Gong

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Anne Moreau

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Michael Hsing

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Sukhbir Kaur

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Liam Worrall

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Emily Amandoron

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Tian Lian

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Linda Jackson

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Jihong Jiang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Lisa Thorson

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Christophe Labriere

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Leonard Foster

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Robert C Brunham

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

William R McMaster

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

B Brett Finlay

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Natalie C Strynadka

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Artem Cherkasov

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Robert N Young

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Neil E Reiner

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

28 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

Antimicrobial Agents and Chemotherapy

23 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

2042-2053

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

Mapping the protein interaction network in methicillin-resistant Staphylococcus aureus.

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Identification of small molecule inhibitors of pyruvate kinase M2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Pyruvate kinase-deficient Escherichia coli exhibits increased plasmid copy number and cyclic AMP levels.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Sulphate removal induces a major conformational change in Leishmania mexicana pyruvate kinase in the crystalline state

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Small and lethal: searching for new antibacterial compounds with novel modes of action

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Pyruvate kinase M2 is a phosphotyrosine-binding protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Antibiotic resistance in bacteria and its future for novel antibiotic development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Resistance to antibiotics: are we in the post-antibiotic era?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Identification of essential genes in Streptococcus pneumoniae by allelic replacement mutagenesis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

ZINC--a free database of commercially available compounds for virtual screening

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Resistance to antimicrobial agents: an update

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

DEG: a database of essential genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Antibacterials: are the new entries enough to deal with the emerging resistance problems?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Pyruvate kinase: current status of regulatory and functional properties

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Genes required for mycobacterial growth defined by high density mutagenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary-phase survival

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Evolutionary rate in the protein interaction network

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Enzymes of carbohydrate metabolism as potential drug targets.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Antimicrobial use and bacterial resistance

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

The allosteric regulation of pyruvate kinase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

The structure of pyruvate kinase from Leishmania mexicana reveals details of the allosteric transition and unusual effector specificity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Discovery and development of new antibiotics: the problem of antibiotic resistance

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Structure of rabbit muscle pyruvate kinase complexed with Mn2+, K+, and pyruvate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Primary structure of three peptides at the catalytic and allosteric sites of the fructose-1,6-bisphosphate-activated pyruvate kinase from Escherichia coli

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Basic local alignment search tool

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Functional analysis, overexpression, and kinetic characterization of pyruvate kinase from methicillin-resistant Staphylococcus aureus.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Identification of novel allosteric regulators of human-erythrocyte pyruvate kinase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Plasmodium falciparum pyruvate kinase as a novel target for antimalarial drug-screening.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Human erythrocyte pyruvate kinase: characterization of the recombinant enzyme and a mutant form (R510Q) causing nonspherocytic hemolytic anemia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088274

Mechanisms of resistance to antibiotics

29 October 2018

1 reference

12 December 2020

Kinetic properties of human muscle pyruvate kinase

1 reference

12 December 2020

Ligand-induced conformational changes in wild-type and mutant yeast pyruvate kinase

1 reference

12 December 2020

Conversion of non-allosteric pyruvate kinase isozyme into an allosteric enzyme by a single amino acid substitution

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.01250-10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357306%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

21357306

1 reference