(Q33832620)

English

Inhibition of tumor growth and metastasis by targeting tumor-associated angiogenesis with antagonists to the receptors of vascular endothelial growth factor

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

Inhibition of tumor growth and metastasis by targeting tumor-associated angiogenesis with antagonists to the receptors of vascular endothelial growth factor (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

0 references

author name string

Zhu Z

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Witte L

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

publication date

1 January 1999

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

195-212

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

https://scigraph.springernature.com/pub.10.1023/a:1006314501634

0 references

Angiostatin induces and sustains dormancy of human primary tumors in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of experimental antiangiogenic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chimeric anti-angiogenin antibody cAb 26-2F inhibits the formation of human breast cancer xenografts in athymic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effects of GBS toxin: a polysaccharide exotoxin from group B beta-hemolytic streptococcus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of microscopic vascularity in benign and malignant prostate tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a soluble vascular endothelial growth factor receptor-immunoglobulin chimera

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extent of tumor vascularization correlates with prognosis and hematogenous metastasis in gastric carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of the microvascular count in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trials of antiangiogenic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in bladder cancer: relationship between microvessel density and tumor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The significance of atypical vessels and neovascularization in cervical neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth and invasion of human melanomas in human skin grafted to immunodeficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vascular endothelial growth factor-induced receptor activation with anti-kinase insert domain-containing receptor single-chain antibodies from a phage display library.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic and predictive value of tumour angiogenesis in ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in cervical neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon gamma-inducible protein 10 (IP-10), a member of the C-X-C chemokine family, is an inhibitor of angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple forms of angiostatin induce apoptosis in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thalidomide is an inhibitor of angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor angiogenesis: therapeutic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor B, a novel growth factor for endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An overview of clinical trials involving inhibitors of angiogenesis and their mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor as a marker of tumor endothelium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological activity and phosphorylation sites of the bacterially expressed cytosolic domain of the KDR VEGF-receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neovascularization in clinical stage A testicular germ cell tumor: prediction of metastatic disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of the sites for ligand binding and receptor dimerization at the extracellular domain of the vascular endothelial growth factor receptor FLT-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial cell proliferation by a peptide corresponding to the exon 7-encoded domain of VEGF165

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined effects of angiostatin and ionizing radiation in antitumour therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flk-1 as a target for tumor growth inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What Is the Evidence That Tumors Are Angiogenesis Dependent?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization of cell surface receptors in signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cancer therapy resistant to resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor tyrosine kinase signaling in vascular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of group B Streptococcus toxin on long-term survival of mice bearing transplanted Madison lung tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of vascular permeability factor (vascular endothelial growth factor) in bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of lasting complete regression of preformed distinct solid tumors by targeting the tumor vasculature using two new anti-endoglin monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VEGF and VEGF-C: specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis and tumor progression of melanoma. Quantification of vascularity in melanocytic nevi and cutaneous malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Troponin I is present in human cartilage and inhibits angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline in combination with chemotherapy or radiation therapy in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis and colonization in the tumor metastatic process: basic and applied advances

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor is a secreted angiogenic mitogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the extracellular domains of Flt-1 that mediate ligand interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis in vivo by interleukin 12.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by interleukin 4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulators of Angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis and tumor metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex roles of matrix metalloproteinases in tumor progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth Inhibition of Murine Melanoma and Human Colon Carcinoma by Recombinant Human Platelet Factor 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional studies on the anti-pathoangiogenic properties of CM101

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of the antineovascularization drug CM101.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1-positive endothelial cell proliferation in vitro and angiogenesis in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Halting angiogenesis suppresses carcinoma cell invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing regulates receptor specificity and activity of VEGF-C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiostatin binds ATP synthase on the surface of human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of neovascularisation to metastasis of non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intratumoral microvessel density and p53 protein: correlation with metastasis in head-and-neck squamous-cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular permeability factor gene expression in normal and neoplastic human ovaries

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of tumor growth with recombinant murine angiostatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor and its receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homologs of vascular endothelial growth factor are encoded by the poxvirus orf virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping of the Sites Involved in Ligand Association and Dissociation at the Extracellular Domain of the Kinase Insert Domain-containing Receptor for Vascular Endothelial Growth Factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The implications of angiogenesis for the biology and therapy of cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of vascular endothelial growth factor in pathological angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunotargeting of liposomes to activated vascular endothelial cells: a strategy for site-selective delivery in the cardiovascular system

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

1 reference

https://pubmed.ncbi.nlm.nih.gov/10665474

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1006314501634

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33832620&oldid=1533540872"