(Q33832641)

29 July 2017

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title

Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results (English)

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29 July 2017

Huang SM

1

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PubMed ID

10665478

29 July 2017

Harari PM

series ordinal

2

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29 July 2017

1 January 1999

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Investigational New Drugs

29 July 2017

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29 July 2017

17

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29 July 2017

3

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29 July 2017

259-269

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https://scigraph.springernature.com/pub.10.1023/a:1006384521198

29 July 2017

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cites work

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12 December 2020

In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor

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12 December 2020

Anti-epidermal growth factor receptor antibodies inhibit the autocrine-stimulated growth of MDA-468 human breast cancer cells.

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12 December 2020

Expression of epidermal growth factor receptor in carcinoma of the cervix

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12 December 2020

Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin

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12 December 2020

In vivo pharmacology and anti-tumour evaluation of the tyrphostin tyrosine kinase inhibitor RG13022.

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12 December 2020

Cell cycle dependence of epidermal growth factor induced radiosensitization

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12 December 2020

Growth inhibition of xenotransplanted human carcinomas by a monoclonal antibody directed against the epidermal growth factor receptor

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12 December 2020

Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy

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12 December 2020

Epidermal growth factor modifies cell cycle control in A431 human squamous carcinoma cells damaged by ionizing radiation.

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12 December 2020

Epidermal growth factor

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12 December 2020

The interaction of epidermal growth factor and radiation in human head and neck squamous cell carcinoma cell lines with vastly different radiosensitivities

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12 December 2020

Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation

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12 December 2020

Advances in radiation therapy for head and neck cancer.

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12 December 2020

Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro

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12 December 2020

Epidermal growth factor receptor overexpression in esophageal carcinoma. An immunohistochemical study correlated with clinicopathologic findings and DNA amplification

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12 December 2020

Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells

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12 December 2020

Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function

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12 December 2020

Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.

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12 December 2020

Epidermal growth factor receptor family and chemosensitization

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12 December 2020

Quantitative estimation of epidermal growth factor receptor and c-erbB-2 in human breast cancer

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12 December 2020

Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.

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12 December 2020

Growth regulation of human renal carcinoma cells: role of transforming growth factor alpha

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12 December 2020

Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice

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12 December 2020

Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications

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12 December 2020

Amplification and overexpression of the epidermal growth factor receptor gene in human renal-cell carcinoma

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12 December 2020

Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma

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12 December 2020

The inducible expression of dominant-negative epidermal growth factor receptor-CD533 results in radiosensitization of human mammary carcinoma cells

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12 December 2020

Epidermal growth factor receptor gene expression in normal human kidney and renal cell carcinoma

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12 December 2020

Signal transduction by receptors with tyrosine kinase activity

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12 December 2020

Tyrosine kinase inhibition: an approach to drug development

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12 December 2020

Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation

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12 December 2020

Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts

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12 December 2020

The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation

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12 December 2020

Amphiregulin anti-sense oligodeoxynucleotides inhibit growth and transformation of a human colon carcinoma cell line

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12 December 2020

Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumors

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12 December 2020

Altered expression of epidermal growth factor receptor and estrogen receptor in MCF-7 cells after single and repeated radiation exposures

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12 December 2020

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody

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12 December 2020

Altered epidermal growth factor signal transduction in activated Ha-ras-transformed human keratinocytes

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12 December 2020

Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells☆☆☆

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12 December 2020

Inhibitory effect of anti-epidermal growth factor receptor antibody on a human gastric cancer.

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12 December 2020

Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors

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12 December 2020

Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model

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12 December 2020

Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies

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12 December 2020

Enhancement of drug sensitivity of human malignancies by epidermal growth factor

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12 December 2020

Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma.

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12 December 2020

Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells

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12 December 2020

Signaling and drug sensitivity

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12 December 2020

Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody

1 reference

12 December 2020

Autonomous proliferation of colon cancer cells that coexpress transforming growth factor alpha and its receptor. Variable effects of receptor-blocking antibody

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12 December 2020

Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin

1 reference

12 December 2020

Infection with a transforming growth factor alpha anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line

1 reference

12 December 2020

The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma

1 reference

12 December 2020

Modulation of tyrosine, serine, and threonine phosphorylation and intracellular processing of the epidermal growth factor receptor by antireceptor monoclonal antibody

1 reference

12 December 2020

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

1 reference

12 December 2020

Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase acti

1 reference

12 December 2020

Prognostic applications of the epidermal growth factor receptor and its ligand, transforming growth factor-alpha.

1 reference

12 December 2020

Regulation of epidermal growth factor receptor in NIH3T3/HER14 cells by antireceptor monoclonal antibodies

1 reference

12 December 2020

Cell growth regulation in epithelial ovarian cancer.

1 reference

12 December 2020

Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A

1 reference

12 December 2020

Anti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145.

1 reference

12 December 2020

Proliferation-independent growth factor modulation of the radiation sensitivity of human prostate cells

1 reference

12 December 2020

Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma.

1 reference

12 December 2020

EGF receptor in neoplasia and metastasis

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12 December 2020

Inhibition of CRIPTO expression and tumorigenicity in human colon cancer cells by antisense RNA and oligodeoxynucleotides.

1 reference

12 December 2020

EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5.

1 reference

12 December 2020

Cooperative inhibition of renal cancer growth by anti-epidermal growth factor receptor antibody and protein kinase A antisense oligonucleotide.

1 reference

12 December 2020

Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies

1 reference

12 December 2020

Mouse/human chimeric monoclonal antibody in man: kinetics and immune response

1 reference

12 December 2020

Receptor protein-tyrosine kinases and their signal transduction pathways

1 reference

12 December 2020

Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225.

1 reference

12 December 2020

Mouse-human chimeric anti-epidermal growth factor receptor antibody C225 inhibits the growth of human renal cell carcinoma xenografts in nude mice

1 reference

12 December 2020

Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in vitro and in nude mice

1 reference

12 December 2020

Dose intensification in curative head and neck cancer radiotherapy--linear quadratic analysis and preliminary assessment of clinical results

1 reference

12 December 2020

Prognostic value of epidermal growth factor receptor expression in cervical carcinoma

1 reference

12 December 2020

Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

12 December 2020

Therapy of human transitional cell carcinoma of the bladder by oral administration of the epidermal growth factor receptor protein tyrosine kinase inhibitor 4,5-dianilinophthalimide

1 reference

12 December 2020

Radiation-induced enhanced proliferation of human squamous cancer cells in vitro: a release from inhibition by epidermal growth factor

1 reference

12 December 2020

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival

1 reference

12 December 2020

Growth inhibition of human colon carcinoma cells by combinations of anti-epidermal growth factor-related growth factor antisense oligonucleotides.

1 reference

12 December 2020

Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1006384521198

1 reference

PubMed ID

10665478

Dimensions Publication ID

29 July 2017

0 references

1 reference

PubMed ID

10665478