(Q33833364)

29 July 2017

1 reference

title

Farnesyltransferase inhibitors. Preclinical development (English)

1 reference

29 July 2017

Kohl NE

1

1 reference

PubMed ID

10667207

29 July 2017

language of work or name

English

0 references

publication date

1 January 1999

1 reference

Annals of the New York Academy of Sciences

29 July 2017

1 reference

29 July 2017

886

1 reference

29 July 2017

91-102

1 reference

The ras gene family and human carcinogenesis

29 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Ras C-terminal processing enzymes--new drug targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

The potential of farnesyltransferase inhibitors as cancer chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Genetic evidence for in vivo cross-specificity of the CaaX-box protein prenyltransferases farnesyltransferase and geranylgeranyltransferase-I in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Direct demonstration of geranylgeranylation and farnesylation of Ki-Ras in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Steady-state kinetic mechanism of Ras farnesyl:protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Pseudodipeptide inhibitors of protein farnesyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Rational design of Ras prenyltransferase inhibitors as potential anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Potent, cell active, non-thiol tetrapeptide inhibitors of farnesyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Novel tricyclic inhibitors of farnesyl protein transferase. Biochemical characterization and inhibition of Ras modification in transfected Cos cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Antitumor 8-chlorobenzocycloheptapyridines: a new class of selective, nonpeptidic, nonsulfhydryl inhibitors of ras farnesylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Phosphinyl acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Hydroxamic acid-based bisubstrate analog inhibitors of Ras farnesyl protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1999.TB09404.X

10.1111/J.1749-6632.1999.TB09404.X

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10667207