(Q33833542)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

MB06322 (CS-917): A potent and selective inhibitor of fructose 1,6-bisphosphatase for controlling gluconeogenesis in type 2 diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Mark D Erion

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Paul D van Poelje

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Srinivas Rao Kasibhatla

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Scott C Potter

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

M Rami Reddy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

K Raja Reddy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Tao Jiang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

William N Lipscomb

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

language of work or name

English

0 references

publication date

23 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

12 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

7970-7975

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

Inhibition of Fructose-1,6-bisphosphatase by a New Class of Allosteric Effectors

12 January 2020

cites work

1 reference

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3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site

4 July 2018

1 reference

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Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography

4 July 2018

1 reference

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New drug targets for type 2 diabetes and the metabolic syndrome

4 July 2018

1 reference

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Pharmacological approaches to inhibit endogenous glucose production as a means of anti-diabetic therapy.

4 July 2018

1 reference

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Review article: Regulation of glucose production with special attention to nonclassical regulatory mechanisms: a review

4 July 2018

1 reference

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Renal gluconeogenesis: its importance in human glucose homeostasis

4 July 2018

1 reference

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Quantitative contributions of gluconeogenesis to glucose production during fasting in type 2 diabetes mellitus

4 July 2018

1 reference

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Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production

4 July 2018

1 reference

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Mechanism by which metformin reduces glucose production in type 2 diabetes

4 July 2018

1 reference

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Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo

4 July 2018

1 reference

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

4 July 2018

1 reference

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Pharmacodynamic profile of a novel inhibitor of the hepatic glucose-6-phosphatase system.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Isolation and characterization of an allelic cDNA for human muscle fructose-1,6-bisphosphatase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Autoregulation of hepatic glucose production

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Glycogen: a carbohydrate source for GLUT-1 glycosylation during glucose deprivation of 3T3-L1 adipocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Hypoglycaemic effect of AICAriboside in mice.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Isolation of a human liver fructose-1,6-bisphosphatase cDNA and expression of the protein in Escherichia coli. Role of ASP-118 and ASP-121 in catalysis

4 July 2018

1 reference

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The allosteric site of human liver fructose-1,6-bisphosphatase. Analysis of six AMP site mutants based on the crystal structure

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

4 July 2018

1 reference

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Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Mechanism of Action of Fructose 1,6‐Bisphosphatase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Inhibition of fructose-1,6-bisphosphatase by fructose 2,6-biphosphate

4 July 2018

1 reference

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Control of gluconeogenesis in liver. I. General features of gluconeogenesis in the perfused livers of rats.

4 July 2018

1 reference

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High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

4 July 2018

1 reference

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Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

4 July 2018

1 reference

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Site-directed mutagenesis of Pro-17 located in the glycine-rich region of adenylate kinase.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Hepatic gluconeogenesis/glycolysis: regulation and structure/function relationships of substrate cycle enzymes

4 July 2018

1 reference

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Conformational transition of fructose-1,6-bisphosphatase: structure comparison between the AMP complex (T form) and the fructose 6-phosphate complex (R form)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study

4 July 2018

1 reference

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Evidence of increased systemic glucose production and gluconeogenesis in an early stage of NIDDM.

4 July 2018

1 reference

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Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502983102

Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502983102

Calculation of relative binding free energy differences for fructose 1,6-bisphosphatase inhibitors using the thermodynamic cycle perturbation approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502983102

Design, synthesis, and characterization of a series of cytochrome P(450) 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502983102

Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502983102

Gluconeogenesis in moderately and severely hyperglycemic patients with type 2 diabetes mellitus

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Efficient hepatic glycogen synthesis in refeeding rats requires continued carbon flow through the gluconeogenic pathway.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138262

Rabbit liver phosphofructokinase. Comparison of some properties with those of muscle phosphofructokinase

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15911772

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intracellular compartmentation and control of alanine metabolism in rat liver parenchymal cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15911772

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition by AICA Riboside of Gluconeogenesis in Isolated Rat Hepatocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15911772

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0502983102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15911772%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference