(Q33838263)

29 July 2017

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title

Gene therapy: the first decade (English)

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29 July 2017

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Mountain A

1

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29 July 2017

1 March 2000

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29 July 2017

Trends in Biotechnology

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29 July 2017

18

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29 July 2017

119-128

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29 July 2017

3

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Germline gene therapy 'must be spared excessive regulation'.

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Viral vectors for gene therapy

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Recombinant vaccinia-PSA (PROSTVAC) can induce a prostate-specific immune response in androgen-modulated human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

The Cambrian period of nonviral gene delivery

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Hyping results 'could damage' gene therapy

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Adenoviral vectors: not to be sneezed at.

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Immune responses to adenovirus and adeno-associated virus in humans.

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Adenovirus complexed with polyethylene glycol and cationic lipid is shielded from neutralizing antibodies in vitro

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Effects of macrophage depletion and anti-CD40 ligand on transgene expression and redosing with recombinant adenovirus

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Blunting of immune responses to adenoviral vectors in mouse liver and lung with CTLA4Ig.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Expression of a retrovirally transduced gene under control of an internal housekeeping gene promoter does not persist due to methylation and is restored partially by 5-azacytidine treatment

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Progress in transcriptionally targeted and regulatable vectors for genetic therapy

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Adeno-associated virus Rep78 protein and terminal repeats enhance integration of DNA sequences into the cellular genome

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Selective uptake and sustained expression of AAV vectors following subcutaneous delivery

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

AAVant-garde gene therapy

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Peroral gene therapy of lactose intolerance using an adeno-associated virus vector

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Adeno-associated virus vectors can be efficiently produced without helper virus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Cytokine gene expression in epidermis with biological effects following injection of naked DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Direct immunologic activities of CpG DNA and implications for gene therapy

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

In vivo transfection of murine lungs with a functioning prokaryotic gene using a liposome vehicle.

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Towards gene therapy for cystic fibrosis: a clinical progress report.

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Prospects for gene therapy for cystic fibrosis

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Safety study and characterization of E1A-liposome complex gene-delivery protocol in an ovarian cancer model

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Transferrin-polycation conjugates as carriers for DNA uptake into cells

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Polyethylenimine-based intravenous delivery of transgenes to mouse lung.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

DNA-based immunization by in vivo transfection of dendritic cells

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Hepatitis B vaccine administration: comparison between jet-gun and syringe and needle

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Phase 1 safety and immune response studies of a DNA vaccine encoding hepatitis B surface antigen delivered by a gene delivery device

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Depth-targeted efficient gene delivery and expression in the skin by pulsed electric fields: an approach to gene therapy of skin aging and other diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Human embryonic stem cells: the future is now

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Molecular switches for regulating therapeutic genes

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Regulated delivery of therapeutic proteins after in vivo somatic cell gene transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

The plasmid replicon of EBV consists of multiple cis-acting elements that facilitate DNA synthesis by the cell and a viral maintenance element

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Safety-modified episomal vectors for human gene therapy.

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Human artificial chromosomes coming into focus

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Stable in vivo gene transduction via a novel adenoviral/retroviral chimeric vector

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Human gene targeting by viral vectors

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

1 reference

7 January 2021

Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

In utero gene therapy: the case against

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

In utero gene therapy: the case for.

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

1 reference

7 January 2021

Gene therapy pushes on, despite doubts

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Congress may block stem-cell research

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

ONYX-015: clinical data are encouraging

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https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-7799%2899%2901416-X

7 January 2021

10.1016/S0167-7799(99)01416-X

Identifiers

DOI

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29 July 2017

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PubMed ID

10675899