(Q33838633)

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Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.

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29 February 2020

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells (English)

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29 February 2020

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29 February 2020

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29 February 2020

Anthony L. Cunningham

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29 February 2020

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29 February 2020

Paul Urquhart Cameron

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29 February 2020

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29 February 2020

Sharon R. Lewin

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29 February 2020

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Ajantha E Solomon

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29 February 2020

Suha Saleh

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29 February 2020

Andrew N Harman

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29 February 2020

Melissa Churchill

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29 February 2020

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1 November 2013

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29 February 2020

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29 February 2020

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29 February 2020

2853-2862

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29 February 2020

18

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29 February 2020

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

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5 July 2018

Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4)

1 reference

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5 July 2018

Targeting the epigenome: effects of epigenetic treatment strategies on genomic stability in healthy human cells

1 reference

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5 July 2018

Randomized phase II trial of erlotinib with and without entinostat in patients with advanced non-small-cell lung cancer who progressed on prior chemotherapy

1 reference

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5 July 2018

Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models

1 reference

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5 July 2018

HIV reservoirs and strategies for eradication

1 reference

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5 July 2018

Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

1 reference

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5 July 2018

HDAC inhibitors in HIV.

1 reference

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5 July 2018

Belinostat: clinical applications in solid tumors and lymphoma

1 reference

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5 July 2018

Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells

1 reference

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5 July 2018

Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells

1 reference

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5 July 2018

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

1 reference

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5 July 2018

Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect

1 reference

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5 July 2018

Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.

1 reference

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5 July 2018

Histone deacetylase inhibitor Scriptaid reactivates latent HIV-1 promoter by inducing histone modification in in vitro latency cell lines.

1 reference

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5 July 2018

Combinatorial latency reactivation for HIV-1 subtypes and variants

1 reference

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5 July 2018

The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro

1 reference

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5 July 2018

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

1 reference

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5 July 2018

Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4079759

5 July 2018

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4079759

5 July 2018

"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4079759

5 July 2018

A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression

1 reference

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5 July 2018

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

1 reference

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5 July 2018

Pharmaceutical approaches to eradication of persistent HIV infection

1 reference

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5 July 2018

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

1 reference

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5 July 2018

A phase I and pharmacokinetic study of the oral histone deacetylase inhibitor, MS-275, in patients with refractory solid tumors and lymphomas

1 reference

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5 July 2018

Histone deacetylase (HDAC) encoding gene expression in pancreatic cancer cell lines and cell sensitivity to HDAC inhibitors.

1 reference

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5 July 2018

PP2A regulates HDAC4 nuclear import

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4079759

5 July 2018

Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes

1 reference

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5 July 2018

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

1 reference

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5 July 2018

Anticancer activities of histone deacetylase inhibitors

1 reference

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A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies

1 reference

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5 July 2018

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

1 reference

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LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression

1 reference

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Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors

1 reference

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IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.

1 reference

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5 July 2018

HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

1 reference

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5 July 2018

Human T cell transcription factor GATA-3 stimulates HIV-1 expression

1 reference

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5 July 2018

Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.

1 reference

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5 July 2018

HIV: Shock and kill.

1 reference

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29 October 2018

CCR7 ligands CCL19 and CCL21 increase permissiveness of resting memory CD4+ T cells to HIV-1 infection: a novel model of HIV-1 latency.

1 reference

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29 October 2018

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

1 reference

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29 October 2018

Identifiers

10.1097/QAD.0000000000000067

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Europe PubMed Central

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29 February 2020

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Europe PubMed Central

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29 February 2020

1 reference

Europe PubMed Central

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29 February 2020

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