(Q33840708)

English

Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Competition of pyruvate with physiological substrates for oxidation by the heart: implications for studies with hyperpolarized [1-13C]pyruvate (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

4

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19 January 2020

author name string

Karlos X Moreno

1

1 reference

Europe PubMed Central

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19 January 2020

Scott M Sabelhaus

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Matthew E Merritt

3

1 reference

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19 January 2020

Craig R Malloy

5

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19 January 2020

publication date

5 March 2010

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19 January 2020

American Journal of Physiology Heart and Circulatory Physiology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

298

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

H1556-64

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Inhibition of carbohydrate oxidation during the first minute of reperfusion after brief ischemia: NMR detection of hyperpolarized 13CO2 and H13CO3-.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Cardiac metabolism measured noninvasively by hyperpolarized 13C MRI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Metabolic imaging and other applications of hyperpolarized 13C1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Real-time metabolic imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Albumin: biochemical properties and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Myocardial metabolism of fatty acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Extraction and release of individual free fatty acids by the heart and fat depots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Pyruvate: metabolic protector of cardiac performance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Preferential uptake of lactate by the normal myocardium in dogs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Six blind men explore an elephant: aspects of fuel metabolism and the control of tricarboxylic acid cycle activity in heart muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Regulation of heart muscle pyruvate dehydrogenase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Deuterium exchange of the methyl group of pyruvate catalyzed by human serum albumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Propionate metabolism in the rat heart by 13C n.m.r. spectroscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Carbon flux through citric acid cycle pathways in perfused heart by 13C NMR spectroscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Contribution of exogenous substrates to acetyl coenzyme A: measurement by 13C NMR under non-steady-state conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Analysis of tricarboxylic acid cycle of the heart using 13C isotope isomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Alterations in substrate utilization in the reperfused myocardium: a direct analysis by 13C NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Regulation of pyruvate dehydrogenase kinase and phosphatase by acetyl-CoA/CoA and NADH/NAD ratios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

5 July 2018

Uniform vascular contrast enhancement and reduced contrast medium volume achieved by using exponentially decelerated contrast material injection method

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Probing the origin of acetyl-CoA and oxaloacetate entering the citric acid cycle from the 13C labeling of citrate released by perfused rat hearts.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Influence of pyruvate on contractile performance and Ca(2+) cycling in isolated failing human myocardium

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Improved systolic and diastolic myocardial function with intracoronary pyruvate in patients with congestive heart failure

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Pyruvate improves cerebral metabolism during hemorrhagic shock

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Pyruvate-enhanced cardioprotection during surgery with cardiopulmonary bypass

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Acute hibernation decreases myocardial pyruvate carboxylation and citrate release

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Acidosis induced by lactate, pyruvate, or HCl increases blood viscosity

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Hemodynamic effects of intravenous pyruvate in the intact, anesthetized dog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2867437

29 October 2018

Effect of Pyruvate and Acetoacetate on the Metabolism of Fatty Acids by the Perfused Rat Heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Fatty Acid and Glucose Metabolism in the Perfused Heart

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00656.2009

21 January 2018

Direct evidence that perhexiline modifies myocardial substrate utilization from fatty acids to lactate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid regulation of glucose metabolism in the intact beating rat heart assessed by carbon-13 NMR spectroscopy: the critical role of pyruvate dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lactic acid and protein interactions: implications for the NMR visibility of lactate in biological systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate selection in the isolated working rat heart: effects of reperfusion, afterload, and concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate augments mechanical function via activation of the pyruvate dehydrogenase complex in reperfused ischemic immature rabbit hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyruvate and lactate metabolism in the in vivo dog heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partitioning of pyruvate between oxidation and anaplerosis in swine hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of pyruvate dehydrogenase in the isolated perfused rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of various substrates to total citric acid cycle flux and anaplerosis as determined by 13C isotopomer analysis and O2 consumption in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of pressure development on membrane transport of glucose in isolated rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 13C mass isotopomer study of anaplerotic pyruvate carboxylation in perfused rat hearts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EFFECT OF KETONE BODIES ON CARDIAC METABOLISM

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Friedreich's ataxia: intravenous pyruvate load to demonstrate a defect in pyruvate metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interconversion of pyruvate dehydrogenase in rat heart muscle upon perfusion with fatty acids or ketone bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20207817

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.00656.2009

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20207817%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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