(Q33845879)

29 July 2017

title

Tenofovir renal proximal tubular toxicity is regulated by OAT1 and MRP4 transporters (English)

1 reference

29 July 2017

1 reference

James J Kohler

1

1 reference

29 July 2017

Seyed H Hosseini

2

1 reference

29 July 2017

Elgin Green

3

1 reference

29 July 2017

Allison Abuin

4

1 reference

29 July 2017

Tomika Ludaway

5

1 reference

29 July 2017

Rodney Russ

6

1 reference

29 July 2017

Robert Santoianni

7

1 reference

29 July 2017

William Lewis

8

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29 July 2017

publication date

14 March 2011

1 reference

29 July 2017

published in

Laboratory Investigation

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29 July 2017

volume

91

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29 July 2017

issue

6

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29 July 2017

page(s)

852-858

1 reference

Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities.

29 July 2017

cites work

1 reference

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Renal impairment in a rural African antiretroviral programme

5 July 2018

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Tenofovir renal toxicity targets mitochondria of renal proximal tubules

5 July 2018

1 reference

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Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation

5 July 2018

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Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.

5 July 2018

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Clinical and genetic determinants of intracellular tenofovir diphosphate concentrations in HIV-infected patients

5 July 2018

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Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination

5 July 2018

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Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution

5 July 2018

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Targeted transgenic overexpression of mitochondrial thymidine kinase (TK2) alters mitochondrial DNA (mtDNA) and mitochondrial polypeptide abundance: transgenic TK2, mtDNA, and antiretrovirals

5 July 2018

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Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma.

5 July 2018

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Mechanism of active renal tubular efflux of tenofovir

5 July 2018

1 reference

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Tenofovir-associated acute and chronic kidney disease: a case of multiple drug interactions

5 July 2018

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Unraveling the racial disparities associated with kidney disease

5 July 2018

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5 July 2018

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Tenofovir disoproxil fumarate: a review of its use in the management of HIV infection

5 July 2018

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Mrp4 confers resistance to topotecan and protects the brain from chemotherapy

5 July 2018

1 reference

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Tubulopathy consecutive to tenofovir-containing antiretroviral therapy in two patients infected with human immunodeficiency virus-1.

5 July 2018

1 reference

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Renal tubular dysfunction associated with tenofovir therapy: report of 7 cases

5 July 2018

1 reference

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5 July 2018

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The molecular pharmacology of organic anion transporters: from DNA to FDA?

5 July 2018

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Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

5 July 2018

1 reference

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Novel aspects of renal organic anion transporters

5 July 2018

1 reference

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5 July 2018

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Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103636

Transport, metabolism and elimination mechanisms of anti-HIV agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103636

Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103636

The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103636

Mitochondrial myopathy caused by long-term zidovudine therapy

5 July 2018

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Renal safety of tenofovir in HIV treatment-experienced patients.

5 July 2018

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Tenofovir DF in antiretroviral-experienced patients: results from a 48-week, randomized, double-blind study

21 January 2018

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Low frequency of renal function impairment during one-year of therapy with tenofovir-containing regimens in the real-world: a case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

Assessment of renal abnormalities in 107 HIV patients treated with tenofovir

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

Association between ABCC2 gene haplotypes and tenofovir-induced proximal tubulopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice

21 January 2018

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Characterization of mice lacking the multidrug resistance protein MRP2 (ABCC2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

Tubular transporters and clearance of adefovir

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2011.48

Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21403643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21403643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Involvement of multiple transporters in the oral absorption of nucleoside analogues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21403643

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LABINVEST.2011.48

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference