(Q33848756)

29 July 2017

title

Proteolysis of monocyte CD14 by human leukocyte elastase inhibits lipopolysaccharide-mediated cell activation (English)

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ORCID Public Data File 2021

29 July 2017

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author name string

K Le-Barillec

1

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29 July 2017

M Si-Tahar

2

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29 July 2017

V Balloy

3

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29 July 2017

M Chignard

4

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29 July 2017

language of work or name

English

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publication date

1 April 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

103

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29 July 2017

issue

7

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29 July 2017

page(s)

1039-1046

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Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide

29 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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Elimination, blocking, and activation of macrophages: three of a kind?

5 July 2018

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5 July 2018

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5 July 2018

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Human neutrophil elastase proteolytically activates the platelet integrin alphaIIbbeta3 through cleavage of the carboxyl terminus of the alphaIIb subunit heavy chain. Involvement in the potentiation of platelet aggregation

5 July 2018

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Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor.

5 July 2018

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5 July 2018

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Monocyte deactivation--rationale for a new therapeutic strategy in sepsis

5 July 2018

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Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion

5 July 2018

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CD14 is a cell-activating receptor for bacterial peptidoglycan

5 July 2018

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5 July 2018

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5 July 2018

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Lipoteichoic acid preparations of gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway.

5 July 2018

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Thrombin functions as an inflammatory mediator through activation of its receptor

5 July 2018

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The phospholipase C/protein kinase C pathway is involved in cathepsin G-induced human platelet activation: comparison with thrombin

5 July 2018

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5 July 2018

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Neutrophil proteinase cathepsin G is proteolytically active on the human platelet glycoprotein Ib-IX receptor: characterization of the cleavage sites within the glycoprotein Ib alpha subunit.

5 July 2018

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Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide.

5 July 2018

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Release of interleukin-8, interleukin-6, and colony-stimulating factors by upper airway epithelial cells: implications for cystic fibrosis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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CD14 is a pattern recognition receptor

5 July 2018

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CD14: physical properties and identification of an exposed site that is protected by lipopolysaccharide

5 July 2018

1 reference

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Serum-independent binding of lipopolysaccharide to human monocytes is trypsin sensitive and does not involve CD14.

5 July 2018

1 reference

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Human leukocyte elastase, cathepsin G, and lactoferrin: family of neutrophil granule glycoproteins that bind to an alveolar macrophage receptor

5 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 July 2018

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Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase

5 July 2018

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The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage

5 July 2018

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Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B

5 July 2018

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Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells

5 July 2018

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Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

5 July 2018

1 reference

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Cathepsin-G and leukocyte elastase inactivate human tumor necrosis factor and lymphotoxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Shedding as a mechanism of down-modulation of CD14 on stimulated human monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Plasma levels of elastase-specific fibrinopeptides correlate with proteinase inhibitor phenotype. Evidence for increased elastase activity in subjects with homozygous and heterozygous deficiency of alpha 1-proteinase inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Activation and damage of cultured airway epithelial cells by human elastase and cathepsin G

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Surface expression of Fc gamma receptor III (CD16) on chemoattractant-stimulated neutrophils is determined by both surface shedding and translocation from intracellular storage compartments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408261

Cationic neutrophil proteins increase transendothelial albumin movement

5 July 2018

1 reference

12 December 2020

Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis

1 reference

12 December 2020

Specific sensitivity of CD43 to neutrophil elastase

1 reference

12 December 2020

Enhancement of cathepsin G-induced platelet activation by leukocyte elastase: consequence for the neutrophil-mediated platelet activation

1 reference

12 December 2020

The role of neutrophil elastase in chronic inflammation

1 reference

12 December 2020

The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease

1 reference

12 December 2020

Quantum proteolysis resulting from release of single granules by human neutrophils: a novel, nonoxidative mechanism of extracellular proteolytic activity

1 reference

12 December 2020

Increased spontaneous release of tumour necrosis factor-alpha by alveolar macrophages from wheezy infants

1 reference

12 December 2020

Sensitive responses of leukocytes to lipopolysaccharide require a protein distinct from CD14 at the cell surface

1 reference

12 December 2020

Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI5779

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29 July 2017

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29 July 2017

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