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The adenomatous polyposis coli protein
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The adenomatous polyposis coli protein
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
main subject
polyposis
1 reference
based on heuristic
inferred from title
author name string
Näthke IS
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
language of work or name
English
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publication date
1 August 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
published in
Journal of Clinical Pathology
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
volume
52
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
page(s)
169-173
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
cites work
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
A domain within the tumor suppressor protein APC shows very similar biochemical properties as the microtubule-associated protein tau.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Identification of four distinct pools of catenins in mammalian cells and transformation-dependent changes in catenin distributions among these pools
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
beta-catenin is a target for the ubiquitin-proteasome pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Dynamics of beta-catenin interactions with APC protein regulate epithelial tubulogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Lessons from hereditary colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Forced expression of the tumor suppressor adenomatosis polyposis coli protein induces disordered cell migration in the intestinal epithelium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Functional interaction of beta-catenin with the transcription factor LEF-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Apoptosis and APC in colorectal tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Association of the APC tumor suppressor protein with catenins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Association of the APC gene product with beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
The APC gene product associates with microtubules in vivo and promotes their assembly in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Wild-type but not mutant APC associates with the microtubule cytoskeleton.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Inactivation of both APC alleles in human and mouse tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Mutations in the APC gene and their implications for protein structure and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
The molecular basis of Turcot's syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
APC binds to the novel protein EB1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Making the connection: cytoskeletal rearrangements during growth cone guidance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
Identification and characterization of the familial adenomatous polyposis coli gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
APC mutations occur early during colorectal tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
5 July 2018
beta-TrCP is a negative regulator of Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Expression of beta-catenin and the adenomatous polyposis coli tumour suppressor protein in mouse neocortical cells in vitro.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Sulindac causes rapid regression of preexisting tumors in Min/+ mice independent of prostaglandin biosynthesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
The cellular distribution of the adenomatous polyposis coli tumour suppressor protein in neuroblastoma cells is regulated by microtubule dynamics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Phosphorylation of the tumor suppressor adenomatous polyposis coli (APC) by the cyclin-dependent kinase p34.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Upregulation of the APC gene product during neuronal differentiation of rat pheochromocytoma PC12 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395695
retrieved
29 October 2018
Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10694935
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cellular mechanisms of wingless/Wnt signal transduction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10694935
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The sulfide metabolite of sulindac prevents tumors and restores enterocyte apoptosis in a murine model of familial adenomatous polyposis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10694935
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Loss of Apc+ in intestinal adenomas from Min mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10694935
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10694935
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1136/MP.52.4.169
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
PMCID
395695
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
PubMed ID
10694935
1 reference
stated in
Europe PubMed Central
PubMed ID
10694935
retrieved
29 July 2017
ResearchGate publication ID
12620541
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