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Finally, CTLA4Ig graduates to the clinic
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
title
Finally, CTLA4Ig graduates to the clinic
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
author name string
M H Sayegh
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
language of work or name
English
0 references
publication date
1 May 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
volume
103
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
issue
9
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
page(s)
1223-1225
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
cites work
CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Homeostasis and self-tolerance in the immune system: turning lymphocytes off.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Is CTLA-4 a master switch for peripheral T cell tolerance?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
The in vivo mechanism of action of CTLA4Ig
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
CTLA-4 ligation blocks CD28-dependent T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Signals and signs for lymphocyte responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
CTLA-4 can function as a negative regulator of T cell activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
CTLA-4 is a second receptor for the B cell activation antigen B7
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
5 July 2018
The role of CD80, CD86, and CTLA4 in alloimmune responses and the induction of long-term allograft survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
Acquired thymic tolerance: role of CTLA4 in the initiation and maintenance of tolerance in a clinically relevant autoimmune disease model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
The role of T-cell costimulatory activation pathways in transplant rejection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
Distinct mechanisms for the induction and maintenance of allograft tolerance with CTLA4-Fc treatment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
T-cell costimulatory blockade in experimental chronic cardiac allograft rejection: effects of cyclosporine and donor antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
CD28-B7 costimulatory blockade by CTLA4Ig prevents actively induced experimental autoimmune encephalomyelitis and inhibits Th1 but spares Th2 cytokines in the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408363
retrieved
29 October 2018
A cell culture model for T lymphocyte clonal anergy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10225963
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
CD28 costimulation prevents cell death during primary T cell activation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10225963
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10225963
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI6952
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
PMCID
408363
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
PubMed ID
10225963
1 reference
stated in
Europe PubMed Central
PubMed ID
10225963
retrieved
29 July 2017
ResearchGate publication ID
13072434
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