(Q33853117)

29 July 2017

title

Short ragweed allergen induces eosinophilic lung disease in HLA-DQ transgenic mice (English)

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ORCID Public Data File 2021

29 July 2017

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1 reference

author name string

S P Chapoval

1

1 reference

29 July 2017

G H Nabozny

2

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29 July 2017

E V Marietta

3

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29 July 2017

E L Raymond

4

1 reference

29 July 2017

C J Krco

5

1 reference

29 July 2017

A G Andrews

6

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29 July 2017

C S David

7

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29 July 2017

language of work or name

English

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publication date

1 June 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

103

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29 July 2017

issue

12

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29 July 2017

page(s)

1707-1717

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The genetics and complexity of allergy and asthma

29 July 2017

cites work

1 reference

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5 July 2018

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HLA transgenic mice as humanized mouse models of disease and immunity.

5 July 2018

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5 July 2018

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HLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis in transgenic mice. Implications in human rheumatoid arthritis

5 July 2018

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Prevention of experimental myasthenia gravis by nasal administration of synthetic acetylcholine receptor T epitope sequences

5 July 2018

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5 July 2018

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5 July 2018

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Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice

5 July 2018

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Interleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma

5 July 2018

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Costimulation through B7-2 (CD86) is required for the induction of a lung mucosal T helper cell 2 (TH2) immune response and altered airway responsiveness

5 July 2018

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Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins

5 July 2018

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Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice

5 July 2018

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Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

5 July 2018

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T-cell responses to allergens: epitope-specificity and clinical relevance.

5 July 2018

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Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors

5 July 2018

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5 July 2018

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Beta 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses

5 July 2018

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The importance of leukotrienes in airway inflammation in a mouse model of asthma

5 July 2018

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T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila

5 July 2018

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Expression and function of HLA-DQ8 (DQA1*0301/DQB1*0302) genes in transgenic mice

5 July 2018

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Mite allergy, clinical atopy, and restriction by HLA class II immune response genes

5 July 2018

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Chemokines active on eosinophils: potential roles in allergic inflammation

5 July 2018

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A role for Th2 T-memory cells in early airway obstruction.

5 July 2018

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HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis

5 July 2018

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Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

5 July 2018

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Atopic profile of inner-city asthma with a comparative analysis on the cockroach-sensitive and ragweed-sensitive subgroups

5 July 2018

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The importance of eosinophils in the immunology of asthma and allergic disease

5 July 2018

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The association of HLA-DR3 with specific IgE to inhaled acid anhydrides

5 July 2018

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HLA-Dw2: a genetic marker for human immune response to short ragweed pollen allergen Ra5. I. Response resulting primarily from natural antigenic exposure

5 July 2018

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Ragweed hay fever: genetic control and linkage to HL-A haplotypes

5 July 2018

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Expression of MHC antigens in normal human lungs and transplanted lungs with obliterative bronchiolitis.

5 July 2018

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The distribution of MHC class I and II antigens on bronchial epithelium

5 July 2018

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Eosinophilic Inflammation in Asthma

5 July 2018

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Class II major histocompatibility complex restriction of human T cell responses to short ragweed allergen, Amb a V.

5 July 2018

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Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse.

5 July 2018

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Changes in the cellular profile of induced sputum after allergen-induced asthmatic responses

5 July 2018

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Studies of the HLA class II alleles involved in human responses to ragweed allergens Ambrosia artemisiifolia V (Ra5S) and Ambrosia trifida V (Ra5G)

5 July 2018

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CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

B7-CD28/CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway responses to inhaled antigens

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

Blockade of CD28/B7 co-stimulation by mCTLA4-Hgamma1 inhibits antigen-induced lung eosinophilia but not Th2 cell development or recruitment in the lung

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

Central role of immunoglobulin (Ig) E in the induction of lung eosinophil infiltration and T helper 2 cell cytokine production: inhibition by a non-anaphylactogenic anti-IgE antibody

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

Importance of interleukin-4 and interleukin-12 in allergen-induced airway changes in mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

HLA Class II Genes in Soybean Epidemic Asthma Patients

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408385

Immediate and late inflammatory responses to ragweed antigen challenge of the peripheral airways in allergic asthmatics. Cellular, mediator, and permeability changes

29 October 2018

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12 December 2020

Airway hyperresponsiveness, increased intracellular spaces of bronchial epithelium, and increased infiltration of eosinophils and lymphocytes in bronchial mucosa in asthma

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12 December 2020

HLA-DR and ICAM-1 expression on bronchial epithelial cells in asthma and chronic bronchitis

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12 December 2020

Functional and phenotypic characteristics of bronchial epithelial cells obtained by brushing from asthmatic and normal subjects

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12 December 2020

Characterization of a murine model of allergic pulmonary inflammation

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12 December 2020

Role of cationic proteins in the airway. Hyperresponsiveness due to airway inflammation

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12 December 2020

Regulation and function of adhesion molecule expression by human alveolar epithelial cells

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12 December 2020

Early-type hypersensitivity-associated airway inflammation and eosinophilia induced by Dermatophagoides farinae in sensitized mice

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12 December 2020

Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography

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12 December 2020

CD23 deficient mice develop allergic airway hyperresponsiveness following sensitization with ovalbumin

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12 December 2020

T-Cell repertoire in the blood and lungs of atopic asthmatics before and after ragweed challenge

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12 December 2020

HLA antigens in asthmatic children

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12 December 2020

HLA-DQ6 and HLA-DQ8 transgenic mice respond to ragweed allergens and recognize a distinct set of epitopes on short and giant ragweed group 5 antigens

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12 December 2020

Elevated levels of the eosinophil granule major basic protein in the sputum of patients with bronchial asthma

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12 December 2020

Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma

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12 December 2020

Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response

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12 December 2020

Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization

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T-lymphocytes regulate genetically determined airway hyperresponsiveness in mice

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Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes

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Identifiers

DOI

10.1172/JCI6175

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29 July 2017

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29 July 2017

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