(Q33855994)

29 July 2017

1 reference

title

The ErbB receptors as targets for breast cancer therapy (English)

1 reference

29 July 2017

Albanell J

1

1 reference

PubMed ID

10705918

29 July 2017

Baselga J

series ordinal

2

1 reference

29 July 2017

1 October 1999

1 reference

Journal of Mammary Gland Biology and Neoplasia

29 July 2017

1 reference

29 July 2017

4

1 reference

29 July 2017

4

1 reference

29 July 2017

337-351

1 reference

https://scigraph.springernature.com/pub.10.1023/a:1018762216147

29 July 2017

0 references

cites work

p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

1 reference

12 December 2020

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts

1 reference

12 December 2020

Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth

1 reference

12 December 2020

ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms

1 reference

12 December 2020

Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment

1 reference

12 December 2020

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

1 reference

12 December 2020

Transgenic mice reveal roles for TGFalpha and EGF receptor in mammary gland development and neoplasia

1 reference

12 December 2020

A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors

1 reference

12 December 2020

Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.

1 reference

12 December 2020

Tumor epidermal growth factor receptor studies in patients with non-small-cell lung cancer or head and neck cancer treated with monoclonal antibody RG 83852

1 reference

12 December 2020

Regulation of signal transduction and signal diversity by receptor oligomerization

1 reference

12 December 2020

Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.

1 reference

12 December 2020

The biology of erbB-2/neu/HER-2 and its role in cancer

1 reference

12 December 2020

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

1 reference

12 December 2020

Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor

1 reference

12 December 2020

Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma

1 reference

12 December 2020

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

12 December 2020

Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies

1 reference

12 December 2020

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

12 December 2020

Tyrosine kinase inhibition: an approach to drug development

1 reference

12 December 2020

Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies

1 reference

12 December 2020

Specific inhibition of epidermal growth factor receptor tyrosine kinase by 4-anilinoquinazolines

1 reference

12 December 2020

Receptor blockade with monoclonal antibodies as anti-cancer therapy

1 reference

12 December 2020

An intramembrane modulator of the ErbB2 receptor tyrosine kinase that potentiates neuregulin signaling

1 reference

12 December 2020

Dose-dense therapy with weekly 1-hour paclitaxel infusions in the treatment of metastatic breast cancer

1 reference

12 December 2020

Characterization of estrogen responsive transforming activity in human breast cancer cell lines

1 reference

12 December 2020

Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

1 reference

12 December 2020

p185c-erbB-2 signal enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair.

1 reference

12 December 2020

Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

1 reference

12 December 2020

Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin

1 reference

12 December 2020

In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product

1 reference

12 December 2020

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody

1 reference

12 December 2020

Regulation of phosphorylation of the c-erbB-2/HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cells

1 reference

12 December 2020

ErbB receptors and EGF-like ligands: cell lineage determination and oncogenesis through combinatorial signaling

1 reference

12 December 2020

The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors

1 reference

12 December 2020

Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors

1 reference

12 December 2020

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.

1 reference

12 December 2020

Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model

1 reference

12 December 2020

Enhanced anti-proliferative activity of the combination of tamoxifen plus HER-2-neu antibody

1 reference

12 December 2020

Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies

1 reference

12 December 2020

1 reference

12 December 2020

Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs

1 reference

12 December 2020

Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells

1 reference

12 December 2020

Characterization of epidermal growth factor receptor and action on human breast cancer cells in culture

1 reference

12 December 2020

Expression of the erbB-2 family of growth factor receptors and their ligands in breast cancers. Implication for tumor biology and clinical behavior.

1 reference

12 December 2020

Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis

1 reference

12 December 2020

Characterization of a growth factor that binds exclusively to the erbB-2 receptor and induces cellular responses

1 reference

12 December 2020

Presence of epidermal growth factor receptor as an indicator of poor prognosis in patients with breast cancer

1 reference

12 December 2020

Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin

1 reference

12 December 2020

Receptors for epidermal growth factor and other polypeptide mitogens

1 reference

12 December 2020

The epidermal growth factor receptor in breast cancer.

1 reference

12 December 2020

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

1 reference

12 December 2020

Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli

1 reference

12 December 2020

ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer

1 reference

12 December 2020

Epidermal-growth-factor receptors and oestrogen receptors in human breast cancer

1 reference

12 December 2020

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen

1 reference

12 December 2020

Inhibitors of tyrosine kinase

1 reference

12 December 2020

Amphiregulin, epidermal growth factor receptor, and estrogen receptor expression in human primary breast cancer

1 reference

12 December 2020

Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site.

1 reference

12 December 2020

Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase acti

1 reference

12 December 2020

1 reference

12 December 2020

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

1 reference

12 December 2020

Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A

1 reference

12 December 2020

Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product

1 reference

12 December 2020

Reciprocal changes in p27(Kip1) and p21(Cip1) in growth inhibition mediated by blockade or overstimulation of epidermal growth factor receptors

1 reference

12 December 2020

Anti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic cancer cell line DU145.

1 reference

12 December 2020

Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma.

1 reference

12 December 2020

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

1 reference

12 December 2020

Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase

1 reference

12 December 2020

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

1 reference

12 December 2020

Humanization of an anti-p185HER2 antibody for human cancer therapy

1 reference

12 December 2020

Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies

1 reference

12 December 2020

PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner

1 reference

12 December 2020

Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells

1 reference

12 December 2020

Roles of ErbB-3 and ErbB-4 in the physiology and pathology of the mammary gland

1 reference

12 December 2020

Augmentation of a humanized anti-HER2 mAb 4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor mAb C225

1 reference

12 December 2020

Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in vitro and in nude mice

1 reference

12 December 2020

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

1 reference

12 December 2020

Dynamic expression and activation of ERBB receptors in the developing mouse mammary gland

1 reference

12 December 2020

Identification of heregulin, a specific activator of p185erbB2

1 reference

12 December 2020

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

1 reference

12 December 2020

Phase I trial and tumour localisation of the anti-EGFR monoclonal antibody ICR62 in head and neck or lung cancer

1 reference

12 December 2020

Immunodetection of the Ligand-Activated Receptor for Epidermal Growth Factor

1 reference

12 December 2020

Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy

1 reference

12 December 2020

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1018762216147

1 reference

PubMed ID

10705918

Dimensions Publication ID

29 July 2017

0 references

1 reference

PubMed ID

10705918