(Q33857449)

29 July 2017

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title

The human mast cell tryptase tetramer: a fascinating riddle solved by structure (English)

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29 July 2017

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C P Sommerhoff

1

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29 July 2017

W Bode

2

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29 July 2017

G Matschiner

3

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29 July 2017

A Bergner

4

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29 July 2017

H Fritz

5

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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Biochimica et Biophysica Acta

29 July 2017

published in

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29 July 2017

volume

1477

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29 July 2017

issue

1-2

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29 July 2017

page(s)

75-89

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Chloroacyl esters as histochemical substrates

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

An enzyme in mast cells with properties like chymotrypsin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Histochemical Demonstration of a Species-Specific Trypsin-like Enzyme in Mast Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Proteolytic enzymes of mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

A new enzyme that specifically inactivates apo-protein of pyridoxal enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Studies on new intracellular proteases in various organs of rat. 1. Purification and comparison of their properties

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Immunofluorescent localization of a serine protease in rat small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

A major serine protease in rat skeletal muscle: Evidence for its mast cell origin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Purification and partial characterization of an α-chymotrypsin-like protease of rat peritoneal mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Purification of an atypical mast cell protease and its levels in developing rats

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Covalent structure of a group-specific protease from rat small intestine. Appendix: Crystallographic data for a group specific protease from rat intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Crystallization and amino acid composition of a serine protease from rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The structure of rat mast cell protease II at 1.9-A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

1 reference

7 January 2021

Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Chymotrypsin- and trypsin-type serine proteases in rat mast cells: properties and functions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Rat mast cell tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Rat peritoneal mast cell carboxypeptidase: localization, purification, and enzymatic properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Rat mast cell carboxypeptidase: amino acid sequence and evidence of enzyme activity within mast cell granules

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Two types of human mast cells that have distinct neutral protease compositions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Ultrastructural and immunohistochemical characterization of normal mast cells at multiple body sites

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Cloning and characterization of complementary DNA for human tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Cloning and characterization of a second complementary DNA for human tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

A novel heparin-dependent processing pathway for human tryptase. Autocatalysis followed by activation with dipeptidyl peptidase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Human mast cell tryptase isoforms: separation and examination of substrate-specificity differences

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Identification and characterization of multiple forms of tryptase from human mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Expression and purification of recombinant human tryptase in a baculovirus system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Of mites and men: trypsin-like proteases in the lungs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Natural disruption of the mouse mast cell protease 7 gene in the C57BL/6 mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Mast cell tryptases: examination of unusual characteristics by multiple sequence alignment and molecular modeling

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Packaging of proteases and proteoglycans in the granules of mast cells and other hematopoietic cells. A cluster of histidines on mouse mast cell protease 7 regulates its binding to heparin serglycin proteoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Regulation of human mast cell tryptase. Effects of enzyme concentration, ionic strength and the structure and negative charge density of polysaccharides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Regulation of the activity of secreted human lung mast cell tryptase by mast cell proteoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Inactivation of human lung tryptase: evidence for a re-activatable tetrameric intermediate and active monomers

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Spontaneous inactivation of human lung tryptase as probed by size-exclusion chromatography and chemical cross-linking: dissociation of active tetrameric enzyme into inactive monomers is the primary event of the entire process

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Structural changes associated with the spontaneous inactivation of the serine proteinase human tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Spontaneous inactivation of human tryptase involves conformational changes consistent with conversion of the active site to a zymogen-like structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Structural basis of the activation and action of trypsin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. II. The binding of the pancreatic trypsin inhibitor and of isoleucine-valine and of sequentially related peptides to trypsinogen and to p-guanidinobenzoate-tryp

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Molecular interaction between factor VII and tissue factor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Self-compartmentalizing proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Degradation of Airway Neuropeptides by Human Lung Tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Human mast cell tryptase attenuates the vasodilator activity of calcitonin gene-related peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Human mast cell proteases hydrolyze neurotensin, kinetensin and Leu5-enkephalin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Effect of human mast cell tryptase on human plasma proenzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The effect of tryptase from human mast cells on human prekallikrein

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Interaction of human low molecular weight kininogen with human mast cell tryptase.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Tryptase and kinin generation: tryptase from human mast cells does not activate human urinary prokallikrein

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

A novel mechanism for bradykinin production at inflammatory sites. Diverse effects of a mixture of neutrophil elastase and mast cell tryptase versus tissue and plasma kallikreins on native and oxidized kininogens.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Human mast cell tryptase fibrinogenolysis: kinetics, anticoagulation mechanism, and cell adhesion disruption

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Identification of human lung mast cell kininogenase as tryptase and relevance of tryptase kininogenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Pericellular substrates of human mast cell tryptase: 72,000 dalton gelatinase and fibronectin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Catabolism of intact type VI collagen microfibrils: susceptibility to degradation by serine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Identification of potential activators of proteinase-activated receptor-2

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Interactions of mast cell tryptase with thrombin receptors and PAR-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Reaction of mast cell proteases tryptase and chymase with protease activated receptors (PARs) on keratinocytes and fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The three-dimensional structure of recombinant leech-derived tryptase inhibitor in complex with trypsin. Implications for the structure of human mast cell tryptase and its inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Design of potent selective zinc-mediated serine protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Interactions of human mast cell tryptase with biological protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Localization and interaction of bovine pancreatic trypsin inhibitor and tryptase in the granules of bovine mast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Lactoferrin, a potent tryptase inhibitor, abolishes late-phase airway responses in allergic sheep

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Neutrophil myeloperoxidase is a potent and selective inhibitor of mast cell tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Histone-tryptase interaction: H2A N-terminal tail removal and inhibitory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Tryptase mediates hyperresponsiveness in isolated guinea pig bronchi

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Sheep mast cell proteinase-1: characterization as a member of a new class of dual-specific ruminant chymases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Purification, characterization and biological evaluation of recombinant leech-derived tryptase inhibitor (rLDTI) expressed at high level in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Evidence for multiple interacting binding sites in bovine tryptase

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Structure of leech derived tryptase inhibitor (LDTI-C) in solution

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

Isolation and characterization of hirustasin, an antistasin-type serine-proteinase inhibitor from the medical leech Hirudo medicinalis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

A new structural class of serine protease inhibitors revealed by the structure of the hirustasin-kallikrein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

A carboxypeptidase inhibitor from the medical leech Hirudo medicinalis. Isolation, sequence analysis, cDNA cloning, recombinant expression, and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

LEKTI, a novel 15-domain type of human serine proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

The mast cell--a fascinating riddle

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4838%2899%2900265-4

7 January 2021

10.1016/S0167-4838(99)00265-4

Identifiers

DOI

1 reference

29 July 2017

1 reference