(Q33862993)

29 July 2017

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title

Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation (English)

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29 July 2017

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1 reference

Lutterbach B

1

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29 July 2017

Hiebert SW

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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29 July 2017

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29 July 2017

volume

245

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29 July 2017

issue

2

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29 July 2017

page(s)

223-235

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The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates

29 July 2017

cites work

1 reference

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7 January 2021

Negative regulation of granulocytic differentiation in the myeloid precursor cell line 32Dcl3 by ear-2, a mammalian homolog of Drosophila seven-up, and a chimeric leukemogenic gene, AML1/ETO.

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7 January 2021

Groucho-dependent and -independent repression activities of Runt domain proteins

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7 January 2021

Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex

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7 January 2021

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

1 reference

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7 January 2021

Functional analysis of the individual enhancer core sequences of polyomavirus: cell-specific uncoupling of DNA replication from transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Failure of embryonic hematopoiesis and lethal hemorrhages in mouse embryos heterozygous for a knocked-in leukemia gene CBFB-MYH11.

1 reference

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7 January 2021

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9

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https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

A transcriptional co-repressor that interacts with nuclear hormone receptors

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https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The capacity of polyomavirus enhancer binding protein 2alphaB (AML1/Cbfa2) to stimulate polyomavirus DNA replication is related to its affinity for the nuclear matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Patterning of cells in the Drosophila eye by Lozenge, which shares homologous domains with AML1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The Drosophila segmentation gene runt acts as a position-specific numerator element necessary for the uniform expression of the sex-determining gene Sex-lethal

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Inhibition of DNA replication factor RPA by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Regulation of LEF-1/TCF transcription factors by Wnt and other signals

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

ETS-core binding factor: a common composite motif in antigen receptor gene enhancers

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Dosage requirements for runt in the segmentation of Drosophila embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Specific transcription factors stimulate simian virus 40 and polyomavirus origins of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The transactivator proteins VP16 and GAL4 bind replication factor A.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Solution structure of core binding factor beta and map of the CBF alpha binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Histone acetylation: a possible mechanism for the inheritance of cell memory at mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The Drosophila segmentation gene runt encodes a novel nuclear regulatory protein that is also expressed in the developing nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Cytoplasmic sequestration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor alpha (CBFalpha) subunit by the leukemia-related PEBP2/CBFbeta-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Premature expression of the macrophage colony-stimulating factor receptor on a multipotential stem cell line does not alter differentiation lineages controlled by stromal cells used for coculture

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The AML1/ETO fusion protein activates transcription of BCL-2

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Transcriptional regulation during myelopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

A large variety of alternatively spliced and differentially expressed mRNAs are encoded by the human acute myeloid leukemia gene AML1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The acidic transcriptional activation domains of VP16 and p53 bind the cellular replication protein A and stimulate in vitro BPV-1 DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Indirect and direct disruption of transcriptional regulation in cancer: E2F and AML-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Transcriptionally active chimeric gene derived from the fusion of the AML1 gene and a novel gene on chromosome 8 in t(8;21) leukemic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The AML1 Gene in the 8;21 and 3;21 Translocations in Chronic and Acute Myeloid Leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

A phorbol ester response element within the human T-cell receptor beta-chain enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): evidence for a new myc collaborating oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Histone acetylation and transcriptional regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Molecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Three distinct domains in TEL-AML1 are required for transcriptional repression of the IL-3 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Histone acetylation: chromatin in action

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Identification of human granzyme B promoter regulatory elements interacting with activated T-cell-specific proteins: implication of Ikaros and CBF binding sites in promoter activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1)

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

A novel transcript encoding an N-terminally truncated AML1/PEBP2 alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2800%2900014-7

7 January 2021

10.1016/S0378-1119(00)00014-7

Identifiers

DOI

1 reference

29 July 2017

1 reference