(Q33864554)

29 July 2017

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title

Antisense therapeutics in chronic myeloid leukaemia: the promise, the progress and the problems (English)

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29 July 2017

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Clark RE

1

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29 July 2017

publication date

1 March 2000

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29 July 2017

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29 July 2017

volume

14

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29 July 2017

issue

3

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29 July 2017

page(s)

347-355

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A triploblast origin for Myxozoa?

29 July 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Gene therapy -- promises, problems and prospects

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7 January 2021

Clinical applications of ribozymes

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7 January 2021

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

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7 January 2021

Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

A novel method to stabilise antisense oligonucleotides against exonuclease degradation.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

The effects of thymidine on deoxyribonucleotide pool levels, cytotoxicity and mutation induction in Friend mouse erythroleukaemia cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Apoptosis induced by adenosine in human leukemia HL-60 cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Potential use of purine nucleosides and enzyme inhibitors for selective depletion of Thy-lymphoblasts from human bone marrow

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Aptameric inhibition of p210bcr-abl tyrosine kinase autophosphorylation by oligodeoxynucleotides of defined sequence and backbone structure

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Biochemical and biological effects of nonionic nucleic acid methylphosphonates

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

An antisense Bcr-Abl phosphodiester-tailed methylphosphonate oligonucleotide reduces the growth of chronic myeloid leukaemia patient cells by a non-antisense mechanism

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Effects of sequence of thioated oligonucleotides on cultured human mammary epithelial cells.

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Mechanism of cellular uptake of modified oligodeoxynucleotides containing methylphosphonate linkages

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Characteristics of oligonucleotide uptake in human keratinocyte cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Poor cellular uptake of antisense oligodeoxynucleotides: an obstacle to their use in chronic myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3'-terminus and their interaction with DNA within mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Oligonucleotides encapsulated in pH sensitive liposomes are efficient toward Friend retrovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Use of an antisense oligonucleotide to inhibit expression of a mutated human procollagen gene (COL1A1) in transfected mouse 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Inhibition of P210BCR/ABL Expression in K562 Cells by Electroporation with an Antisense Oligonucleotide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Use of cell-free retroviral vector preparations for transduction of cells from the marrow of chronic phase and blast crisis chronic myelogenous leukemia patients and from normal individuals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Retroviral gene transfer to primitive normal and leukemic hematopoietic cells using clinically applicable procedures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Retroviral mediated gene transfer in chronic myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Single base discrimination for ribonuclease H-dependent antisense effects within intact human leukaemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Nuclear delivery of antisense oligodeoxynucleotides through reversible permeabilization of human leukemia cells with streptolysin O.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Preclinical studies of streptolysin-O in enhancing antisense oligonucleotide uptake in harvests from chronic myeloid leukaemia patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

The molecular genetics of Philadelphia chromosome-positive leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Selective Inhibition of Leukemia Cell Proliferation by BCR-ABL Antisense Oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Dominant negative MYC blocks transformation by ABL oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Differential complementation of Bcr-Abl point mutants with c-Myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Isolation and characterization of the human cellular myc gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Tumour-specific inhibition of lymphoma growth by an antisense oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

G1/S transition in normal human T-lymphocytes requires the nuclear protein encoded by c-myb

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Characterization of the v-myb DNA binding domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Differentiation of mouse erythroleukemia cells enhanced by alternatively spliced c-myb mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Clinical use of streptolysin-O to facilitate antisense oligodeoxyribonucleotide delivery for purging autografts in chronic myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Two doses of paclitaxel and statistical analysis: try, try, try again

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Antisense oligonucleotides: towards clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

A more efficient and specific strategy in the ablation of mRNA in Xenopus laevis using mixtures of antisense oligos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Second-generation antisense oligonucleotides: structure-activity relationships and the design of improved signal-transduction inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Gene inhibition using antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401677

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2401677

1 reference

Dimensions Publication ID

29 July 2017

1038477429

0 references

1 reference