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A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
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Europe PubMed Central
PMC publication ID
116068
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
title
A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author
Daniel Besser
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
J F Bromberg
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2
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
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8 December 2019
J E Darnell
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3
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Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
H Hanafusa
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
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8 December 2019
language of work or name
English
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publication date
1 February 1999
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
Molecular and Cellular Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
19
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
1401-1409
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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A receptor tyrosine kinase, Sky, and its ligand Gas 6 are expressed in gonads and support primordial germ cell growth or survival in culture.
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Expression of tyrosine kinase gene in mouse thymic stromal cells
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Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases
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Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.
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Rek, a gene expressed in retina and brain, encodes a receptor tyrosine kinase of the Axl/Tyro3 family
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28 July 2018
Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain
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Unique signal transduction of Eyk: constitutive stimulation of the JAK-STAT pathway by an oncogenic receptor-type tyrosine kinase
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28 July 2018
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
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Gas6, the ligand of Axl tyrosine kinase receptor, has mitogenic and survival activities for serum starved NIH3T3 fibroblasts
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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
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28 July 2018
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
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28 July 2018
The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation
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28 July 2018
Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts
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28 July 2018
Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase
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Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei.
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28 July 2018
Molecular cloning of a novel receptor tyrosine kinase, tif, highly expressed in human ovary and testis
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28 July 2018
Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain
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28 July 2018
brt, a mouse gene encoding a novel receptor-type protein-tyrosine kinase, is preferentially expressed in the brain
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28 July 2018
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer
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28 July 2018
Epidermal growth factor and lipopolysaccharide activate Stat3 transcription factor in mouse liver.
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28 July 2018
Receptor protein-tyrosine kinases and their signal transduction pathways
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28 July 2018
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
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28 July 2018
The receptor tyrosine kinase ARK mediates cell aggregation by homophilic binding
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28 July 2018
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
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28 July 2018
Production of high-titer helper-free retroviruses by transient transfection
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28 July 2018
SH2 domains recognize specific phosphopeptide sequences
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28 July 2018
Role of LFB3 in cell-specific cAMP induction of the urokinase-type plasminogen activator gene
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28 July 2018
The MAPK signaling cascade
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28 July 2018
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
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28 July 2018
Jak-STAT signaling induced by the v-abl oncogene
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28 July 2018
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
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28 July 2018
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
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28 July 2018
Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein
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28 July 2018
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
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28 July 2018
A novel putative tyrosine kinase receptor with oncogenic potential
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28 July 2018
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase
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28 July 2018
Involvement of p21ras in activation of extracellular signal-regulated kinase 2.
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28 July 2018
A novel oncogene, v-ryk, encoding a truncated receptor tyrosine kinase is transduced into the RPL30 virus without loss of viral sequences
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28 July 2018
Activation of c-Src in cells bearing v-Crk and its suppression by Csk
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28 July 2018
The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
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28 July 2018
The murine ufo receptor: molecular cloning, chromosomal localization and in situ expression analysis
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28 July 2018
Rat cell line 3y1 and its virogenic polyoma- and SV40-transformed derivatives
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28 July 2018
Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB.
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29 October 2018
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.
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29 October 2018
Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase
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29 October 2018
NYK/FLK-1: a putative receptor protein tyrosine kinase isolated from E10 embryonic neuroepithelium is expressed in endothelial cells of the developing embryo.
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29 October 2018
Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase.
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29 October 2018
The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases
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PubMed Central
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29 October 2018
Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=116068
retrieved
29 October 2018
Cloning and developmental expression analysis of the murine c-mer tyrosine kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=116068
retrieved
29 October 2018
rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=116068
retrieved
29 October 2018
The proto-oncogene of v-eyk (v-ryk) is a novel receptor-type protein tyrosine kinase with extracellular Ig/GN-III domains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=116068
retrieved
29 October 2018
GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9891073
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.2.1401
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PMC publication ID
116068
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed publication ID
9891073
1 reference
stated in
Europe PubMed Central
PMC publication ID
116068
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9891073%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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