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Loss of fibroblast HIF-1α accelerates tumorigenesis.
scientific article
Loss of fibroblast HIF-1α accelerates tumorigenesis
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Europe PubMed Central
PMCID
4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
title
Loss of fibroblast HIF-1α accelerates tumorigenesis
(English)
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PMCID
4089958
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31 January 2020
author
Jung-whan Kim
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1
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Europe PubMed Central
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4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
Yun Sok Lee
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5
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PMCID
4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
Christian Stockmann
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6
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4089958
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31 January 2020
Michael C. Ostrowski
series ordinal
10
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4089958
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31 January 2020
Randall S. Johnson
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11
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PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
author name string
Colin Evans
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2
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Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Alexander Weidemann
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3
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PMCID
4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
Norihiko Takeda
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4
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4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Cristina Branco-Price
series ordinal
7
1 reference
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Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
Filip Brandberg
series ordinal
8
1 reference
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Europe PubMed Central
PMCID
4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
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31 January 2020
Gustavo Leone
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9
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Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
language of work or name
English
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3 May 2012
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Europe PubMed Central
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4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
published in
Cancer Research
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Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
volume
72
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stated in
Europe PubMed Central
PMCID
4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
issue
13
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stated in
Europe PubMed Central
PMCID
4089958
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
page(s)
3187-3195
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Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4089958/fullTextXML
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cites work
Vessel abnormalization: another hallmark of cancer? Molecular mechanisms and therapeutic implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Tumors as organs: complex tissues that interface with the entire organism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Loss of myeloid cell-derived vascular endothelial growth factor accelerates fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Pten in stromal fibroblasts suppresses mammary epithelial tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Co-evolution of tumor cells and their microenvironment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Acute postnatal ablation of Hif-2alpha results in anemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Macrophages regulate the angiogenic switch in a mouse model of breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Fibroblasts in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Stromal fibroblasts in cancer initiation and progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Progression to Malignancy in the Polyoma Middle T Oncoprotein Mouse Breast Cancer Model Provides a Reliable Model for Human Diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Targeting HIF-1 for cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Inflammation and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Putting tumours in context
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Identification and characterization of a fibroblast marker: FSP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
5 July 2018
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
29 October 2018
Flt-1 signaling in macrophages promotes glioma growth in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
29 October 2018
Tumor-associated macrophages press the angiogenic switch in breast cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
29 October 2018
Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
29 October 2018
Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
29 October 2018
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1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4089958
retrieved
29 October 2018
VEGF is required for growth and survival in neonatal mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22556263
retrieved
12 December 2020
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Identifiers
DOI
10.1158/0008-5472.CAN-12-0534
1 reference
stated in
Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PMCID
4089958
1 reference
stated in
Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
PubMed ID
22556263
1 reference
stated in
Europe PubMed Central
PMCID
4089958
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22556263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 January 2020
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