(Q33877066)

29 July 2017

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title

Genetic modulation of tumor antigen presentation (English)

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29 July 2017

Xu M

1

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29 July 2017

Qiu G

2

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29 July 2017

Jiang Z

3

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29 July 2017

von Hofe E

4

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29 July 2017

Humphreys RE

5

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29 July 2017

publication date

1 April 2000

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29 July 2017

published in

Trends in Biotechnology

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29 July 2017

volume

18

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29 July 2017

issue

4

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29 July 2017

page(s)

167-172

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https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901421-9

29 July 2017

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Tumor immunotherapy: cytokines and antigen presentation

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The role of CD4+ T cell responses in antitumor immunity

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The central role of CD4(+) T cells in the antitumor immune response

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Tumor antigen presentation: changing the rules

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Class II-transfected tumor cells directly present endogenous antigen to CD4+ T cells in vitro and are APCs for tumor-encoded antigens in vivo.

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Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

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MHC class II-transfected tumor cells induce long-term tumor-specific immunity in autologous mice.

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Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity

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Cancer immunotherapy by antisense suppression of Ii protein in MHC-class-II-positive tumor cells

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Molecular mechanisms used by tumors to escape immune recognition: immunogenetherapy and the cell biology of major histocompatibility complex class I.

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Lack of class II transactivator causes severe deficiency of HLA-DR expression in small cell lung cancer

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Invariant chain expression in colon neoplasms

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Correlation of HLA-D/Ii antigen expression in breast carcinoma with local lymphohistiocytic infiltration reveals considerable dysregulation in a subset of tumors

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Effect of gamma interferon on HLA class-I and -II transcription and protein expression in human breast adenocarcinoma cell lines

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Lymphoid monoclonal antibodies reactive with lung tumors. Diagnostic applications

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Analysis of epithelial and lymphoid phenotypic markers in relation to growth pattern of colorectal adenomas

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Expression of HLA-A,B,C, beta 2-microglobulin (beta 2m), HLA-DR, -DP, -DQ and of HLA-D-associated invariant chain (Ii) in soft-tissue tumors

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MHC class II antigen-associated invariant chain on renal cell cancer may contribute to the anti-tumor immune response of the host

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Identification of hairy cell leukemia subset defining p35 as the human homologue of Ii

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Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

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Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

1 reference

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7 January 2021

HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells

1 reference

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7 January 2021

Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain

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https://api.crossref.org/works/10.1016%2FS0167-7799%2800%2901421-9

7 January 2021

The invariant chain inhibits presentation of endogenous antigens by a human fibroblast cell line

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In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM

1 reference

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Mice lacking the MHC class II-associated invariant chain

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A segment of the MHC class II beta chain plays a critical role in targeting class II molecules to the endocytic pathway

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Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chain

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A novel antigen-processing-defective phenotype in major histocompatibility complex class II-positive CIITA transfectants is corrected by interferon-gamma

1 reference

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7 January 2021

Does B7-1 expression confer antigen-presenting cell capacity to tumors in vivo?

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Expression of MHC Class II and B7-1 and B7-2 costimulatory molecules accompanies tumor rejection and reduces the metastatic potential of tumor cells

1 reference

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7 January 2021

10.1016/S0167-7799(00)01421-9

Identifiers

DOI

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29 July 2017

1 reference