(Q33877323)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

0 references

5

1 reference

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18 March 2020

author name string

Laureen C Colis

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Christina M Woo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Denise C Hegan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Zhenwu Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Seth B Herzon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

publication date

11 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

6

1 reference

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18 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

504-510

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice

18 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

The diazofluorene antitumor antibiotics: structural elucidation, biosynthetic, synthetic, and chemical biological studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Natural products containing a diazo group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Quinone methide chemistry of prekinamycins: 13C-labeling, spectral global fitting and in vitro studies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Mechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin F

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Studies on the mechanism of action of prekinamycin, a member of the diazoparaquinone family of natural products: evidence for both sp2 radical and orthoquinonemethide intermediates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Kinamycins A and C, bacterial metabolites that contain an unusual diazo group, as potential new anticancer agents: antiproliferative and cell cycle effects

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

A proposal for the mechanism-of-action of diazoparaquinone natural products

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

The comet assay for DNA damage and repair: principles, applications, and limitations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Mechanisms of in situ activation for DNA-targeting antitumor agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

C8-arylguanine and C8-aruladenine formation in calf thymus DNA from arenediazonium ions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

A new antibiotic, kinamycin: fermentation, isolation, purification and properties

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Structures and Biological Properties of Kinamycin A, B, C, and D

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Role of free radicals and catalytic metal ions in human disease: an overview

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

The carbohydrate domain of calicheamicin gamma I1 determines its sequence specificity for DNA cleavage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

DNA double-strand breaks and alkali-labile bonds produced by bleomycin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

Diazo group electrophilicity in kinamycins and lomaiviticin A: potential insights into the molecular mechanism of antibacterial and antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

Kinamycin-mediated DNA cleavage under biomimetic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

Kinamycin F downregulates cyclin D3 in human leukemia K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

BRCA1 and BRCA2: different roles in a common pathway of genome protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4090708

Analysis of kinamycin D-mediated DNA cleavage

29 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1944

A new antibiotic, kinamycin

21 January 2018

1 reference

12 December 2020

Isolation of Lomaiviticins C–E, Transformation of Lomaiviticin C to Lomaiviticin A, Complete Structure Elucidation of Lomaiviticin A, and Structure–Activity Analyses

1 reference

12 December 2020

Bioactivation as a model for drug design bioreductive alkylation

1 reference

12 December 2020

Biosynthesis of the Kinamycins

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEM.1944

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

24848236

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24848236%20AND%20SRC:MED&resulttype=core&format=json