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The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
review article
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Europe PubMed Central
title
The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
main subject
Saccharomyces cerevisiae
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author
Marc R. Gartenberg
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
author name string
Gartenberg MR
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1
1 reference
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Europe PubMed Central
PubMed publication ID
10744999
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29 July 2017
publication date
1 April 2000
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Europe PubMed Central
PubMed publication ID
10744999
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
published in
Current Opinion in Microbiology
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
3
1 reference
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
2
1 reference
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
132-137
1 reference
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Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Telomeric chromatin modulates replication timing near chromosome ends
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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Silencing and heritable domains of gene expression
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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Mating-type gene switching in Saccharomyces cerevisiae
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https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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Mechanisms of silencing in Saccharomyces cerevisiae
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https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III
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https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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Persistence of an alternate chromatin structure at silenced loci in vitro
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The conserved core of a human SIR2 homologue functions in yeast silencing
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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inferred from DOI database lookup
Transcriptional silencing in yeast is associated with reduced nucleosome acetylation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sum1 and Hst1 repress middle sporulation-specific gene expression during mitosis in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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inferred from DOI database lookup
sir2 mutants of Kluyveromyces lactis are hypersensitive to DNA-targeting drugs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
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CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Leishmania major: cell type dependent distribution of a 43 kDa antigen related to silent information regulatory-2 protein family.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
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Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
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DNA in transcriptionally silent chromatin assumes a distinct topology that is sensitive to cell cycle progression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Persistence of an alternate chromatin structure at silenced loci in the absence of silencers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cohabitation of insulators and silencing elements in yeast subtelomeric regions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Limitations of silencing at native yeast telomeres
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast HML I silencer defines a heterochromatin domain boundary by directional establishment of silencing.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The boundaries of the silenced HMR domain in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UASrpg can function as a heterochromatin boundary element in yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear compartments and gene regulation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spreading of transcriptional repressor SIR3 from telomeric heterochromatin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tethered Sir3p nucleates silencing at telomeres and internal loci in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perinuclear localization of chromatin facilitates transcriptional silencing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sir-Ku-itous routes to make ends meet
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast Ku as a regulator of chromosomal DNA end structure
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast cell-type regulation of DNA repair
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct evidence for SIR2 modulation of chromatin structure in yeast rDNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of Sir2p: the nucleolus as a compartment for silent information regulators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An unusual form of transcriptional silencing in yeast ribosomal DNA
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Pch2 links chromatin silencing to meiotic checkpoint control.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AGING INSACCHAROMYCES CEREVISIAE
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Extrachromosomal rDNA circles--a cause of aging in yeast
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Elimination of replication block protein Fob1 extends the life span of yeast mother cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1369-5274%2800%2900064-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1369-5274(00)00064-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
10744999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10744999
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10744999%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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