(Q33883053)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen, Bet v 1, for allergy vaccination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1

1 reference

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19 January 2020

Peter Valent

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Monika Fohr

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Raffaela Campana

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Christian Baumgartner

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Rudolf Valenta

6

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

5 January 2011

1 reference

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19 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

Vaccine

1 reference

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19 January 2020

volume

29

1 reference

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19 January 2020

issue

11

1 reference

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19 January 2020

page(s)

2140-2148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

Inhibition of CD23-dependent facilitated allergen binding to B cells following vaccination with genetically modified hypoallergenic Bet v 1 molecules

19 January 2020

cites work

1 reference

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5 July 2018

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Chemical modification of birch allergen extract leads to a reduction in allergenicity as well as immunogenicity

5 July 2018

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Modifications increasing the efficacy of recombinant vaccines; marked increase in antibody titers with moderately repetitive variants of a therapeutic allergy vaccine

5 July 2018

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A hybrid expressing genetically engineered major allergens of the Parietaria pollen as a tool for specific allergy vaccination

5 July 2018

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Vaccination with genetically engineered allergens prevents progression of allergic disease.

5 July 2018

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Strategies for converting allergens into hypoallergenic vaccine candidates

5 July 2018

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From allergen structure to new forms of allergen-specific immunotherapy

5 July 2018

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Nasal challenges with recombinant derivatives of the major birch pollen allergen Bet v 1 induce fewer symptoms and lower mediator release than rBet v 1 wild-type in patients with allergic rhinitis.

5 July 2018

1 reference

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The future of antigen-specific immunotherapy of allergy

5 July 2018

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Naturally processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC interactions.

5 July 2018

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Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity

5 July 2018

1 reference

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Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper

5 July 2018

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Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Modulation of the allergic immune response in BALB/c mice by subcutaneous injection of high doses of the dominant T cell epitope from the major birch pollen allergen Bet v 1.

5 July 2018

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 July 2018

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Studies on the effect of the carrier molecule on antihapten antibody synthesis. II. Carrier specificity of anti-2,4-dinitrophenyl-poly-l-lysine antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing anti-hapten antibody responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Peptide and protein molecular weight determination by electrophoresis using a high-molarity tris buffer system without urea

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Calculation of protein extinction coefficients from amino acid sequence data

5 July 2018

1 reference

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Use of T7 RNA polymerase to direct expression of cloned genes

5 July 2018

1 reference

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Recombinant allergens for immunoblot diagnosis of tree-pollen allergy

5 July 2018

1 reference

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Profilins constitute a novel family of functional plant pan-allergens.

5 July 2018

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A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1.

5 July 2018

1 reference

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Analysis of epitope-specific immune responses induced by vaccination with structurally folded and unfolded recombinant Bet v 1 allergen derivatives in man.

29 October 2018

1 reference

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Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.

29 October 2018

1 reference

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Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults

29 October 2018

1 reference

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A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.

29 October 2018

1 reference

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Non-anaphylactic surface-exposed peptides of the major birch pollen allergen, Bet v 1, for preventive vaccination.

29 October 2018

1 reference

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Vaccines for birch pollen allergy based on genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Recombinant allergens promote expression of CD203c on basophils in sensitized individuals

29 October 2018

1 reference

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Nonanaphylactic synthetic peptides derived from B cell epitopes of the major grass pollen allergen, Phl p 1, for allergy vaccination.

29 October 2018

1 reference

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Recombinant allergens with reduced allergenicity but retaining immunogenicity of the natural allergens: hybrids of yellow jacket and paper wasp venom allergen antigen 5s.

29 October 2018

1 reference

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High-level expression and purification of the major birch pollen allergen, Bet v 1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Cytokine and Antibody Responses in Birch-Pollen-Allergic Patients Treated with Genetically Modified Derivatives of the Major Birch Pollen Allergen Bet v 1

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Clinical effects of immunotherapy with genetically modified recombinant birch pollen Bet v 1 derivatives

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Comparison of inflammatory responses to genetically engineered hypoallergenic derivatives of the major birch pollen allergen Bet v 1 and to recombinant Bet v 1 wild type in skin chamber fluids collected from birch pollen–allergic patients

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4092211

Safety of allergen-specific immunotherapy. Relation between dosage regimen, allergen extract, disease and systemic side-effects during induction treatment

10 December 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: results obtained with a mix of two recombinant Bet v 1 fragments and recombinant Bet v 1 trimer in a Swedish population before the

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Comparison of genetically engineered hypoallergenic rBet v 1 derivatives with rBet v 1 wild-type by skin prick and intradermal testing: results obtained in a French population

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Developments in allergen-specific immunotherapy: from allergen extracts to allergy vaccines bypassing allergen-specific immunoglobulin E and T cell reactivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Combination vaccines for the treatment of grass pollen allergy consisting of genetically engineered hybrid molecules with increased immunogenicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Immunologic characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p2, Phl p 5)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Induction of IgE antibodies in mice and rhesus monkeys with recombinant birch pollen allergens: Different allergenicity of Bet v 1 and Bet v 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

Allergenicity, immunogenicity and dose-relationship of three intact allergen vaccines and four allergoid vaccines for subcutaneous grass pollen immunotherapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VACCINE.2010.12.080

10.1016/J.VACCINE.2010.12.080

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21215346%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21215346

1 reference