(Q33885078)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

A dilated cardiomyopathy troponin C mutation lowers contractile force by reducing strong myosin-actin binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

main subject

dilated cardiomyopathy

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

David Dweck

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Daniel P Reynaldo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

James D Potter

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

6 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

17371-17379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

Clinical and functional characterization of TNNT2 mutations identified in patients with dilated cardiomyopathy

30 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Mutations in the cardiac Troponin C gene are a cause of idiopathic dilated cardiomyopathy in childhood.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Molecular and cellular aspects of troponin cardiomyopathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

The molecular genetic basis for hypertrophic cardiomyopathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Calcium regulation in the human myocardium affected by dilated cardiomyopathy: a structural basis for impaired Ca2+-sensitivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Separation of subfragment-1 isoenzymes from rabbit skeletal muscle myosin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878500

Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064105

Challenging current paradigms related to cardiomyopathies. Are changes in the Ca2+ sensitivity of myofilaments containing cardiac troponin C mutations (G159D and L29Q) good predictors of the phenotypic outcomes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064105

Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064105

Expanding the range of free calcium regulation in biological solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.064105

Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy

21 January 2018

1 reference

12 December 2020

The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation

1 reference

12 December 2020

Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies

1 reference

12 December 2020

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy

1 reference

12 December 2020

The off rate of Ca(2+) from troponin C is regulated by force-generating cross bridges in skeletal muscle

1 reference

12 December 2020

Binding of heavy meromyosin and subfragment-1 to thin filaments in myofibrils and single muscle fibers

1 reference

12 December 2020

The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase

1 reference

12 December 2020

Purification of muscle actin

1 reference

12 December 2020

Binary interactions of troponin subunits

1 reference

12 December 2020

Effect of rigor and cycling cross-bridges on the structure of troponin C and on the Ca2+ affinity of the Ca2+-specific regulatory sites in skinned rabbit psoas fibers

1 reference

12 December 2020

Reciprocal coupling between troponin C and myosin crossbridge attachment

1 reference

12 December 2020

A direct regulatory role for troponin T and a dual role for troponin C in the Ca2+ regulation of muscle contraction

1 reference

12 December 2020

Regulation of the cross-bridge transition from a weakly to strongly bound state in skinned rabbit muscle fibers

1 reference

12 December 2020

Fluorescent probes attached to Cys 35 or Cys 84 in cardiac troponin C are differentially sensitive to Ca(2+)-dependent events in vitro and in situ

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.064105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371872%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

20371872

1 reference