(Q33885249)

29 July 2017

title

Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue Thr101. (English)

1 reference

29 July 2017

Zhen Tao

1

1 reference

29 July 2017

Noa Rosental

2

1 reference

29 July 2017

Baruch I Kanner

3

1 reference

29 July 2017

Armanda Gameiro

4

1 reference

29 July 2017

Juddy Mwaura

5

1 reference

29 July 2017

Christof Grewer

6

1 reference

29 July 2017

language of work or name

English

0 references

publication date

8 April 2010

1 reference

Journal of Biological Chemistry

29 July 2017

published in

1 reference

29 July 2017

volume

285

1 reference

29 July 2017

issue

23

1 reference

29 July 2017

page(s)

17725-17733

1 reference

The equivalent of a thallium binding residue from an archeal homolog controls cation interactions in brain glutamate transporters

29 July 2017

cites work

1 reference

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5 July 2018

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Molecular simulations elucidate the substrate translocation pathway in a glutamate transporter

5 July 2018

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Thallium ions can replace both sodium and potassium ions in the glutamate transporter excitatory amino acid carrier 1

5 July 2018

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Interactions of alkali cations with glutamate transporters

5 July 2018

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Dynamics of the extracellular gate and ion-substrate coupling in the glutamate transporter

5 July 2018

1 reference

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Two conformational changes are associated with glutamate translocation by the glutamate transporter EAAC1.

5 July 2018

1 reference

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Cooperation of the conserved aspartate 439 and bound amino acid substrate is important for high-affinity Na+ binding to the glutamate transporter EAAC1

5 July 2018

1 reference

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Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

5 July 2018

1 reference

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Role of Na+ and K+ in enzyme function

5 July 2018

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Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

The glutamate transporter subtypes EAAT4 and EAATs 1-3 transport glutamate with dramatically different kinetics and voltage dependence but share a common uptake mechanism

5 July 2018

1 reference

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Structure of a glutamate transporter homologue from Pyrococcus horikoshii

5 July 2018

1 reference

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The glutamate and neutral amino acid transporter family: physiological and pharmacological implications

5 July 2018

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Comparison of coupled and uncoupled currents during glutamate uptake by GLT-1 transporters.

5 July 2018

1 reference

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Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters.

5 July 2018

1 reference

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The anion conductance of the glutamate transporter EAAC1 depends on the direction of glutamate transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Substrate translocation kinetics of excitatory amino acid carrier 1 probed with laser-pulse photolysis of a new photolabile precursor of D-aspartic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Glutamate translocation of the neuronal glutamate transporter EAAC1 occurs within milliseconds

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Isolation of current components and partial reaction cycles in the glial glutamate transporter EAAT2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Clearance of glutamate inside the synapse and beyond

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a Chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Flux coupling in a neuronal glutamate transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Binding order of substrates to the (sodium + potassium ion)-coupled L-glutamic acid transporter from rat brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Rapid and efficient site-specific mutagenesis without phenotypic selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Expression of a cloned gamma-aminobutyric acid transporter in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Cloning and expression of a rat brain L-glutamate transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Primary structure and functional characterization of a high-affinity glutamate transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Active transport of L-glutamate by membrane vesicles isolated from rat brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Solubilization and reconstitution of the L-glutamic acid transporter from rat brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Kinetics of a human glutamate transporter.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.121798

Ion fluxes associated with excitatory amino acid transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.121798

Valence screening of water in protein crystals reveals potential Na+ binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.121798

Is the glutamate residue Glu-373 the proton acceptor of the excitatory amino acid carrier 1?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.121798

Voltage-independent sodium-binding events reported by the 4B-4C loop in the human glutamate transporter excitatory amino acid transporter 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.121798

Arginine 445 Controls the Coupling between Glutamate and Cations in the Neuronal Transporter EAAC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.121798

Anion currents and predicted glutamate flux through a neuronal glutamate transporter.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878536

Multiple consequences of mutating two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20378543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glutamate 404 is involved in the substrate discrimination of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20378543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20378543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.121798

1 reference

29 July 2017

1 reference

29 July 2017

1 reference