(Q33886397)

English

The M1 muscarinic agonist CI-1017 facilitates trace eyeblink conditioning in aging rabbits and increases the excitability of CA1 pyramidal neurons.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

The M1 muscarinic agonist CI-1017 facilitates trace eyeblink conditioning in aging rabbits and increases the excitability of CA1 pyramidal neurons (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

author name string

C Weiss

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

A R Preston

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

R D Schwarz

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

D Welty

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

J F Disterhoft

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 January 2000

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

783-790

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

Characterization of a slow cholinergic post-synaptic potential recorded in vitro from rat hippocampal pyramidal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of protein kinase C inhibits cellular production of the amyloid beta-protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacology of cholinergic excitatory responses in hippocampal pyramidal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma Isoform-selective changes in PKC immunoreactivity after trace eyeblink conditioning in the rabbit hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nictitating membrane conditioning to tone in the immobilized albino rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eyeblink conditioning discriminates Alzheimer's patients from non-demented aged

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged Ca2+-dependent afterhyperpolarizations in hippocampal neurons of aged rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central administration of the muscarinic receptor subtype - selective antagonist pirenzepine selectively impairs passive avoidance learning in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivity of pirenzepine in the central nervous system. II. Differential effects of pirenzepine and scopolamine on performance of a representational memory task.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampectomy impairs the memory of recently, but not remotely, acquired trace eyeblink conditioned responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of trace conditioning of the nictitating membrane response in rabbits by central cholinergic blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a preferential involvement of M1 muscarinic receptors in representational memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a family of muscarinic acetylcholine receptor genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of pirenzepine on spatial learning in the Morris Water Maze

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Water-maze learning and effects of cholinergic drugs in mouse strains with high and low hippocampal pyramidal cell counts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the properties of hippocampal pyramidal neurons in the aged rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reflex facilitation of the nictitating membrane response remains after cerebellar lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo evaluation of the subtype-selective muscarinic agonist PD 151832.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Learning-induced afterhyperpolarization reductions in hippocampus are specific for cell type and potassium conductance

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cholinergic hypothesis of geriatric memory dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A system for quantitative analysis of associative learning. Part 1. Hardware interfaces with cross-species applications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic receptors in aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic receptor subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectivity of pirenzepine in the central nervous system. I. Direct autoradiographic comparison of the regional distribution of pirenzepine and carbamylcholine binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer disease: plaques, tangles, and the basal forebrain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease and eyeblink conditioning: 750 ms trace vs. 400 ms delay paradigm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-dependent afterhyperpolarization and learning in young and aging hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metrifonate improves associative learning and retention in aging rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic activity and amyloid precursor protein metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired trace eyeblink conditioning in bilateral, medial-temporal lobe amnesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine induced modulation of hippocampal pyramidal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of nimodipine dose and serum concentration to learning enhancement in aging rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampectomy disrupts trace eye-blink conditioning in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nimodipine facilitates associative learning in aging rabbits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical update

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between heterosynaptic reflex facilitation and acquisition of the nictitating membrane response in control and scopolamine-injected rabbits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classical conditioning in patients with Alzheimer's disease: a multiday study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trace eyeblink conditioning in rabbits demonstrates heterogeneity of learning ability both between and within age groups.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative behavioral and neurochemical activities of cholinergic antagonists in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of spatial learning by the M1 muscarinic antagonist pirenzepine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that Ca/calmodulin-dependent protein kinase mediates the modulation of the Ca2+-dependent K+ current, IAHP, by acetylcholine, but not by glutamate, in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient changes in excitability of rabbit CA3 neurons with a time course appropriate to support memory consolidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A system for quantitative analysis of associative learning. Part 2. Real-time software for MS-DOS microcomputers

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic excitation of mammalian hippocampal pyramidal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of the repetitive discharge of rat CA 1 pyramidal neurones in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of classical conditioning in patients with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylcholine mediates a slow synaptic potential in hippocampal pyramidal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling of ml Muscarinic Receptors to G Protein in Alzheimer Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological mechanisms of cholinergic action in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of hippocampal M1 muscarinic receptors impairs working memory performance of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rabbit preparation for neuro-behavioral auditory research

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10632607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.20-02-00783.2000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772417&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33886397&oldid=1609484930"