(Q33899261)

29 July 2017

1 reference

title

Feedback and hormonal regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: the concept of cholesterol buffering capacity (English)

1 reference

29 July 2017

Ness GC

1

1 reference

PubMed ID

10782041

29 July 2017

Chambers CM

series ordinal

2

1 reference

29 July 2017

1 May 2000

1 reference

Experimental Biology and Medicine

29 July 2017

1 reference

29 July 2017

224

1 reference

29 July 2017

1

1 reference

29 July 2017

8-19

1 reference

beta-Hydroxy-beta-methyl-glutaryl coenzyme A reductase, cleavage and condensing enzymes in relation to cholesterol formation in rat liver

29 July 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Cholesterol modification of hedgehog signaling proteins in animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Regulation of the mevalonate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Effects of monotherapy with an HMG-CoA reductase inhibitor on the progression of coronary atherosclerosis as assessed by serial quantitative arteriography. The Canadian Coronary Atherosclerosis Intervention Trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Molecular dissection of the role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Degradation of HMG-CoA reductase in vitro. Cleavage in the membrane domain by a membrane-bound cysteine protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

A discoordinate increase in the cellular amount of 3-hydroxy-3-methylglutaryl-CoA reductase results in the loss of rate-limiting control over cholesterogenesis in a tumour cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Relative rates of sterol synthesis in the liver and various extrahepatic tissues of normal and cholesterol-fed rabbits. Relationship to plasma lipoprotein and tissue cholesterol levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

The intracellular mechanism responsible for dietary feedback control of cholesterol synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Dietary cholesterol regulates hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in rats primarily at the level of translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

The length of 5'-untranslated leader sequences influences distribution of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in polysomes: effects of lovastatin, oxysterols, and mevalonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 3 beta-hydroxy-lanost-8-en-32-al, an intermediate in the conversion of lanosterol to cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Oxylanosterols as modifiers of cholesterol biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Oligomerization state influences the degradation rate of 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Effects of L-triiodothyronine and the thyromimetic L-94901 on serum lipoprotein levels and hepatic low-density lipoprotein receptor, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and apo A-I gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Evidence that physiologic levels of circulating estrogens and neonatal sex-imprinting modify postpubertal hepatic microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Baseline serum cholestanol as predictor of recurrent coronary events in subgroup of Scandinavian simvastatin survival study. Finnish 4S Investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Inhibitors of Cholesterol Biosynthesis Increase Hepatic Low-Density Lipoprotein Receptor Protein Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Gene Expression by Sterols and Nonsterols in Rat Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors Unmask Cryptic Regulatory Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Inhibitors of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Unmask Transcriptional Regulation of Hepatic Low-Density Lipoprotein Receptor Gene Expression by Dietary Cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Effects of 15-Oxa-32-vinyl-lanost-8-ene-3β,32 diol on the Expression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Low Density Lipoprotein Receptor in Rat Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

Transcriptional Regulation of Rat Hepatic Low-Density Lipoprotein Receptor and Cholesterol 7α Hydroxylase by Thyroid Hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1525-1373.2000.22359.X

10.1046/J.1525-1373.2000.22359.X

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10782041