(Q33900128)

29 July 2017

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title

Rb function in cell-cycle regulation and apoptosis (English)

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29 July 2017

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Harbour JW

1

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29 July 2017

Dean DC

series ordinal

2

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29 July 2017

publication date

1 April 2000

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29 July 2017

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29 July 2017

volume

2

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29 July 2017

issue

4

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29 July 2017

page(s)

E65-7

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Human retinoblastoma susceptibility gene: cloning, identification, and sequence

29 July 2017

cites work

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Structural evidence for the authenticity of the human retinoblastoma gene

21 January 2018

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A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

21 January 2018

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The retinoblastoma protein and cell cycle control

21 January 2018

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Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

21 January 2018

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The regulation of E2F by pRB-family proteins

21 January 2018

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Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells

21 January 2018

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

21 January 2018

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The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

21 January 2018

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21 January 2018

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

21 January 2018

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

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E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product

21 January 2018

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Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

21 January 2018

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Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

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A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

21 January 2018

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Direct transcriptional repression by pRB and its reversal by specific cyclins

21 January 2018

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The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter

21 January 2018

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Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 January 2018

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Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

21 January 2018

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The transcription factor E2F-1 is a downstream target of RB action

21 January 2018

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E2F is required to prevent inappropriate S-phase entry of mammalian cells

21 January 2018

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A rough guide to a smooth brain

21 January 2018

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Chromatin as an essential part of the transcriptional mechanim

21 January 2018

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ATP-dependent remodeling and acetylation as regulators of chromatin fluidity

21 January 2018

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Histone acetylation in chromatin structure and transcription

21 January 2018

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Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs.

21 January 2018

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

21 January 2018

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

21 January 2018

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

21 January 2018

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Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

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Rb interacts with histone deacetylase to repress transcription

21 January 2018

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Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

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RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins

21 January 2018

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The CBP co-activator stimulates E2F1/DP1 activity

21 January 2018

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A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor

21 January 2018

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The "dark side" of chromatin remodeling: repressive effects on transcription

21 January 2018

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Dissecting the regulatory circuitry of a eukaryotic genome

21 January 2018

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Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

21 January 2018

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

21 January 2018

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A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

21 January 2018

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RB and hbrm cooperate to repress the activation functions of E2F1

21 January 2018

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Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

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Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

21 January 2018

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

21 January 2018

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p14ARF links the tumour suppressors RB and p53.

21 January 2018

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 January 2018

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Effects of an Rb mutation in the mouse

21 January 2018

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Requirement for a functional Rb-1 gene in murine development

21 January 2018

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Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development

21 January 2018

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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

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Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

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E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

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SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family

21 January 2018

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7 January 2021

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

1 reference

7 January 2021

Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators

1 reference

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

7 January 2021

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos

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7 January 2021

Identifiers

DOI

10.1038/35008695

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Dimensions Publication ID

29 July 2017

1017716258

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