(Q33901025)

29 July 2017

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title

Identification of PKC-isoform-specific biological actions using pharmacological approaches (English)

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29 July 2017

Way KJ

1

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29 July 2017

Chou E

series ordinal

2

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29 July 2017

King GL

series ordinal

3

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29 July 2017

publication date

1 May 2000

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Trends in Pharmacological Sciences

29 July 2017

published in

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29 July 2017

volume

21

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29 July 2017

issue

5

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29 July 2017

page(s)

181-187

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

29 July 2017

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The extended protein kinase C superfamily

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Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy

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Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart

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Enzymatic rationale and preclinical support for a potent protein kinase C beta inhibitor in cancer therapy

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Protein kinase C-epsilon is responsible for the protection of preconditioning in rabbit cardiomyocytes

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Rottlerin, a novel protein kinase inhibitor

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UCN-01, an anti-tumor drug, is a selective inhibitor of the conventional PKC subfamily

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Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes

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Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C

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(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

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A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats

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In vivo phosphorylation of cardiac troponin I by protein kinase Cbeta2 decreases cardiomyocyte calcium responsiveness and contractility in transgenic mouse hearts

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Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancer

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Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

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7 January 2021

Selective role for beta-protein kinase C in signaling for O-2 generation but not degranulation or adherence in differentiated HL60 cells

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7 January 2021

A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth

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7 January 2021

Activation of the PKC-isotypes alpha, beta 1, gamma, delta and epsilon by phorbol esters of different biological activities

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The phorbol derivatives thymeleatoxin and 12-deoxyphorbol-13-O-phenylacetate-10-acetate cause translocation and down-regulation of multiple protein kinase C isozymes

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7 January 2021

Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents

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C2 Region-derived Peptides Inhibit Translocation and Function of β Protein Kinase C in Vivo

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7 January 2021

A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death

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7 January 2021

A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function

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7 January 2021

Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation

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7 January 2021

An autoregulatory region in protein kinase C: the pseudoanchoring site

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7 January 2021

10.1016/S0165-6147(00)01468-1

Identifiers

DOI

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29 July 2017

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