(Q33902085)

29 July 2017

title

Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin (English)

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29 July 2017

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L I Plotkin

1

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29 July 2017

R S Weinstein

2

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29 July 2017

A M Parfitt

3

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29 July 2017

P K Roberson

4

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29 July 2017

S C Manolagas

5

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29 July 2017

T Bellido

6

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29 July 2017

language of work or name

English

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publication date

1 November 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

104

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29 July 2017

issue

10

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29 July 2017

page(s)

1363-1374

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Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone

29 July 2017

cites work

1 reference

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Onset of apoptotic DNA fragmentation can precede cell elimination by days in the small intestinal villus

5 July 2018

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Cyclic administration of pamidronate in children with severe osteogenesis imperfecta

5 July 2018

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5 July 2018

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5 July 2018

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Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone

5 July 2018

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

5 July 2018

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Sphingosine kinase mediates cyclic AMP suppression of apoptosis in rat periosteal cells

5 July 2018

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The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

5 July 2018

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Inhibition of etoposide-induced apoptosis with peptide aldehyde inhibitors of proteasome

5 July 2018

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Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines

5 July 2018

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DNA binding of the glucocorticoid receptor is not essential for survival

5 July 2018

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Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

5 July 2018

1 reference

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High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein

5 July 2018

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Establishment of an osteocyte-like cell line, MLO-Y4.

5 July 2018

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Prevention of corticosteroid-induced osteoporosis with alendronate in sarcoid patients

5 July 2018

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Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

The structure of bone tissues and the cellular control of their deposition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Parathyroid hormone activates mitogen-activated protein kinase via a cAMP-mediated pathway independent of Ras.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Dissociation of binding and antiresorptive properties of hydroxybisphosphonates by substitution of the hydroxyl with an amino group.

5 July 2018

1 reference

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A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates

5 July 2018

1 reference

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Bisphosphonates: mechanisms of action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Bisphosphonates induce osteoblasts to secrete an inhibitor of osteoclast-mediated resorption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Bisphosphonates act on rat bone resorption through the mediation of osteoblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Stimulation of interleukin-6 production by either calcitonin gene-related peptide or parathyroid hormone in two phenotypically distinct bone marrow-derived murine stromal cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

The effects of 2-year treatment with the aminobisphosphonate alendronate on bone metabolism, bone histomorphometry, and bone strength in ovariectomized nonhuman primates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Risk of vertebral fracture and relationship to bone mineral density in steroid treated rheumatoid arthritis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

A short amino acid sequence able to specify nuclear location

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Inhibition of osteoclast-like cell formation by bisphosphonates in long-term cultures of human bone marrow.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Calcitonin has direct effects on 3[H]-thymidine incorporation and alkaline phosphatase activity in human osteoblast-line cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Effects of calcitonin on 3',5'-cyclic adenosine monophosphate and calcium second messenger generation and osteoblast function in UMR 106-06 osteoblast-like cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Bisphosphonates stimulate formation of osteoblast precursors and mineralized nodules in murine and human bone marrow cultures in vitro and promote early osteoblastogenesis in young and aged mice in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

The effects of androgen deficiency on murine bone remodeling and bone mineral density are mediated via cells of the osteoblastic lineage.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-beta.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Bisphosphonates act on osteoblastic cells and inhibit osteoclast formation in mouse marrow cultures.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Characterization of an osteoblast-like clonal cell line which responds to both parathyroid hormone and calcitonin.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409837

Activation of the Janus kinase/STAT (signal transducer and activator of transcription) signal transduction pathway by interleukin-6-type cytokines promotes osteoblast differentiation

29 October 2018

1 reference

12 December 2020

Prevention of glucocorticoid-induced osteoporosis

1 reference

12 December 2020

Effects of bisphosphonates and inorganic pyrophosphate on osteogenesis in vitro

1 reference

12 December 2020

Changes in bone histomorphometry after long-term treatment with intermittent, cyclic etidronate for postmenopausal osteoporosis

1 reference

12 December 2020

Function of osteocytes in bone

1 reference

12 December 2020

The effects of risedronate on canine cancellous bone remodeling: three-dimensional kinetic reconstruction of the remodeling site

1 reference

12 December 2020

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

1 reference

12 December 2020

CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis

1 reference

12 December 2020

Intravenous administration of alendronate counteracts the in vivo effects of glucocorticoids on bone remodeling

1 reference

12 December 2020

Identification of apoptotic changes in osteocytes in normal and pathological human bone

1 reference

12 December 2020

Exploiting and bypassing the bone remodeling cycle to optimize the treatment of osteoporosis

1 reference

12 December 2020

Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI6800

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29 July 2017

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29 July 2017

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