(Q33902482)

29 July 2017

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title

The mammary gland as a bioreactor: expression, processing, and production of recombinant proteins (English)

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29 July 2017

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Clark AJ

1

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29 July 2017

publication date

1 July 1998

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Journal of Mammary Gland Biology and Neoplasia

29 July 2017

published in

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29 July 2017

volume

3

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29 July 2017

issue

3

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29 July 2017

page(s)

337-350

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Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes

29 July 2017

cites work

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12 December 2020

Production of transgenic rabbits, sheep and pigs by microinjection

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12 December 2020

Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits

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12 December 2020

Generation of transgenic dairy cattle using 'in vitro' embryo production

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12 December 2020

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

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12 December 2020

Transgene rescue in the mammary gland is associated with transcription but does not require translation of BLG transgenes

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12 December 2020

Viable offspring derived from fetal and adult mammalian cells

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12 December 2020

N-glycosylation of recombinant human interferon-gamma produced in different animal expression systems

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12 December 2020

Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts

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12 December 2020

Single-copy transgenic mice with chosen-site integration

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12 December 2020

Transgenic production of a variant of human tissue-type plasminogen activator in goat milk: generation of transgenic goats and analysis of expression

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12 December 2020

Mammalian cDNA and prokaryotic reporter sequences silence adjacent transgenes in transgenic mice

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12 December 2020

Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

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12 December 2020

Introns increase transcriptional efficiency in transgenic mice

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12 December 2020

Rabbit beta-casein promoter directs secretion of human interleukin-2 into the milk of transgenic rabbits

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12 December 2020

Sheep cloned by nuclear transfer from a cultured cell line

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12 December 2020

The 3' untranslated region of bovine preprolactin contains a transferable non-poly(A) mRNA sequence that prolongs translation.

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12 December 2020

Mammary gland expression of transgenes and the potential for altering the properties of milk

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12 December 2020

Transgenic livestock as bioreactors: stable expression of human alpha-1-antitrypsin by a flock of sheep

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12 December 2020

Bovine alpha S1-casein gene sequences direct high level expression of active human urokinase in mouse milk

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12 December 2020

Structural study of the sugar chains of CD36 purified from bovine mammary epithelial cells: occurrence of novel hybrid-type sugar chains containing the Neu5Ac alpha 2-->6GalNAc beta 1-->4GlcNAc and the Man alpha 1-->2Man alpha 1-->3Man alpha 1-->6Ma

1 reference

12 December 2020

Fixing human factor IX (fIX): correction of a cryptic RNA splice enables the production of biologically active fIX in the mammary gland of transgenic mice

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12 December 2020

Composite response elements mediate hormonal and developmental regulation of milk protein gene expression

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12 December 2020

Translational efficiency is regulated by the length of the 3' untranslated region

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12 December 2020

Proteolytic maturation of protein C upon engineering the mouse mammary gland to express furin

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12 December 2020

Locus control region function and heterochromatin-induced position effect variegation

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12 December 2020

Expression of active human clotting factor IX from recombinant DNA clones in mammalian cells

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12 December 2020

Chromosomal position effects and the modulation of transgene expression.

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12 December 2020

Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice

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12 December 2020

Structure and function of milk protein genes

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12 December 2020

Transgenesis in mice by cytoplasmic injection of polylysine/DNA mixtures

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12 December 2020

An analysis of vertebrate mRNA sequences: intimations of translational control

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12 December 2020

Transgenic pigs produce functional human factor VIII in milk

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12 December 2020

High expression of the caprine beta-casein gene in transgenic mice

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12 December 2020

Transcription control: repressed repeats express themselves

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12 December 2020

High-level expression of biologically active human alpha 1-antitrypsin in the milk of transgenic mice

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12 December 2020

High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C

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12 December 2020

Inefficient processing of human protein C in the mouse mammary gland

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12 December 2020

Integration and Stable Germ Line Transmission of Genes Injected into Mouse Pronuclei

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12 December 2020

Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus.

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12 December 2020

Comparable processing of beta-lactoglobulin pre-mRNA in cell culture and transgenic mouse models

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12 December 2020

Alteration of the quality of milk by expression of sheep β-lactoglobulin in transgenic mice

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12 December 2020

High level expression of active human alpha-1-antitrypsin in the milk of transgenic sheep

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12 December 2020

Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans-immortalized hepatic cell lines

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12 December 2020

Prolactin-mediated transcriptional and post-transcriptional control of casein gene expression

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12 December 2020

Targeting expression to the mammary gland: intronic sequences can enhance the efficiency of gene expression in transgenic mice

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12 December 2020

Rescuing transgene expression by co-integration

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12 December 2020

Organization and expression of eucaryotic split genes coding for proteins

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12 December 2020

Transgenic expression of a variant of human tissue-type plasminogen activator in goat milk: purification and characterization of the recombinant enzyme

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12 December 2020

Identifiers

DOI

10.1023/A:1018723712996

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Dimensions Publication ID

29 July 2017

1036999619

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