(Q33903557)

29 July 2017

Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice (English)

1 reference

29 July 2017

1 reference

1 reference

9

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author name string

C Léon

1

1 reference

29 July 2017

B Hechler

2

1 reference

29 July 2017

M Freund

3

1 reference

29 July 2017

A Eckly

4

1 reference

29 July 2017

C Vial

5

1 reference

29 July 2017

P Ohlmann

6

1 reference

29 July 2017

A Dierich

7

1 reference

29 July 2017

M LeMeur

8

1 reference

29 July 2017

C Gachet

10

1 reference

29 July 2017

language of work or name

English

0 references

publication date

1 December 1999

1 reference

Journal of Clinical Investigation

29 July 2017

1 reference

29 July 2017

104

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29 July 2017

1731-1737

1 reference

29 July 2017

12

1 reference

Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Receptors for purines and pyrimidines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Role of P2Y1 purinoceptor in ADP-induced platelet activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Platelet receptors for collagen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Loss of ATP diphosphohydrolase activity with endothelial cell activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

The P2Y purinoceptor in rat brain microvascular endothelial cells couple to inhibition of adenylate cyclase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Identification of competitive antagonists of the P2Y1 receptor.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

The human platelet ADP receptor activates Gi2 proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Cloning and functional expression of a brain G-protein-coupled ATP receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Cloning of rat and mouse P2Y purinoceptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Selective expression of purinoceptor cP2Y1 suggests a role for nucleotide signalling in development of the chick embryo.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Ligand specificity and ticlopidine effects distinguish three human platelet ADP receptors.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Collagen receptor signalling in platelets: extending the role of the ITAM.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

The P2Y1 receptor is necessary for adenosine 5'-diphosphate-induced platelet aggregation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409888

Mouse antithrombotic assay: a simple method for the evaluation of antithrombotic agents in vivo. Potentiation of antithrombotic activity by ethyl alcohol

29 October 2018

1 reference

12 December 2020

ADP receptors on platelets

1 reference

12 December 2020

Restenosis after coronary angioplasty

1 reference

12 December 2020

Presence of P2X1 purinoceptors in human platelets and megakaryoblastic cell lines

1 reference

12 December 2020

Identification of a P2X1 purinoceptor expressed on human platelets

1 reference

12 December 2020

The P2Y1 receptor, necessary but not sufficient to support full ADP-induced platelet aggregation, is not the target of the drug clopidogrel

1 reference

12 December 2020

Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation

1 reference

12 December 2020

The P2Y1 receptor is normal in a patient presenting a severe deficiency of ADP-induced platelet aggregation

1 reference

12 December 2020

No requirement of P2X1 purinoceptors for platelet aggregation

1 reference

12 December 2020

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

1 reference

12 December 2020

Epinephrine potentiates human platelet activation but is not an aggregating agent

1 reference

12 December 2020

Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI8399

1 reference

29 July 2017

1 reference

29 July 2017

1 reference