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Mechanisms of action of cyclosporine.
scientific article published in May 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
review article
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Europe PubMed Central
title
Mechanisms of action of cyclosporine
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
author
Shigeo Koyasu
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
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8 November 2019
author name string
S Matsuda
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1
1 reference
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Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
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8 November 2019
publication date
1 May 2000
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Europe PubMed Central
PubMed ID
10878286
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8 November 2019
published in
Immunopharmacology
1 reference
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Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
volume
47
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
issue
2-3
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
page(s)
119-125
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
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8 November 2019
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Biological effects of cyclosporin A: A new antilymphocytic agent
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Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A
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In situ hybridization for interleukin 2 and interleukin 2 receptor mRNA in T cells activated in the presence or absence of cyclosporin A.
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7 January 2021
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Cyclophilin: a specific cytosolic binding protein for cyclosporin A
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7 January 2021
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Cyclosporine induces cancer progression by a cell-autonomous mechanism.
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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development
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Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes
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7 January 2021
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Cyclosporine
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Role of angiotensin II in the tubulointerstitial fibrosis of obstructive nephropathy
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7 January 2021
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Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription
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Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction
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FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes
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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
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T lymphocyte activation signals for interleukin-2 production involve activation of MKK6-p38 and MKK7-SAPK/JNK signaling pathways sensitive to cyclosporin A
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The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.
1 reference
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7 January 2021
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FK506 and Cyclosporin A Each Inhibit Antigen-Specific Signaling in the T Cell Line 171 in the Absence of a Calcium Signal
1 reference
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7 January 2021
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A viral mechanism for inhibition of the cellular phosphatase calcineurin.
1 reference
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7 January 2021
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A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
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7 January 2021
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NF-AT components define a family of transcription factors targeted in T-cell activation
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FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin
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The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation
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TGF-beta and the endothelium during immune injury
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Transcription factors of the NFAT family: regulation and function
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Networking Rho family GTPases in lymphocytes
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7 January 2021
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AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.
1 reference
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Crossref
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7 January 2021
based on heuristic
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Mitogen-activated protein kinase pathways
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
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Mitogen-activated protein kinases: specific messages from ubiquitous messengers
1 reference
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7 January 2021
based on heuristic
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Protein folding. Prolyl isomerases join the fold
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Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands
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7 January 2021
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Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells
1 reference
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7 January 2021
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Protein serine/threonine phosphatases--new avenues for cell regulation
1 reference
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7 January 2021
based on heuristic
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Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of transforming growth factor-beta 1 in experimental chronic cyclosporine nephropathy
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
JNK is involved in signal integration during costimulation of T lymphocytes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinase cascades and regulation of gene expression
1 reference
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
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Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes
1 reference
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition
1 reference
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporine stimulates expression of transforming growth factor-beta in renal cells. Possible mechanism of cyclosporines antiproliferative effects.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
A functional T-cell receptor signaling pathway is required for p95vav activity
1 reference
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
T cell responses in calcineurin A alpha-deficient mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0162-3109%2800%2900192-2
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0162-3109(00)00192-2
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
PubMed ID
10878286
1 reference
stated in
Europe PubMed Central
PubMed ID
10878286
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878286%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
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