(Q33908498)

29 July 2017

title

Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action (English)

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29 July 2017

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Y J Lidor

1

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29 July 2017

K C O'Briant

2

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29 July 2017

F J Xu

3

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29 July 2017

T C Hamilton

4

1 reference

29 July 2017

R F Ozols

5

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29 July 2017

R C Bast

6

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29 July 2017

language of work or name

English

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publication date

1 November 1993

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

92

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29 July 2017

issue

5

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29 July 2017

page(s)

2440-2447

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Protein measurement with the Folin phenol reagent

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Reactivity of a monoclonal antibody with human ovarian carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Glutathione metabolism as a determinant of therapeutic efficacy: a review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Glutathione transferases: an overview

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

The cellular heterogeneity of malignant neoplasms: implications for adjuvant chemotherapy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Elimination of malignant clonogenic cells from human bone marrow using multiple monoclonal antibodies and complement.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Characterization of immunotoxins active against ovarian cancer cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

New aspects of clinical drug resistance: the role of gene amplification and the reversal of resistance in drug refractory cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Membrane transport alterations as a mechanism of resistance to anticancer agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Concerns about ovarian epithelial cancer management.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Formation and repair of cisplatin-induced adducts to DNA in cultured normal and repair-deficient human fibroblasts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Pseudomonas exotoxin coupled to a monoclonal antibody against ovarian cancer inhibits the growth of human ovarian cancer cells in a mouse model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Recombinant ricin A chain conjugated to monoclonal antibodies: improved tumor cell inhibition in the presence of lysosomotropic compounds

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Non-chemotherapeutic agents that potentiate chemotherapy efficacy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Lymphocyte proliferation in glutathione-depleted lymphocytes: direct relationship between glutathione availability and the proliferative response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Effect of glutathione on DNA repair in cisplatin-resistant human ovarian cancer cell lines.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Use of immunotoxins in combination to inhibit clonogenic growth of human breast carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Schedule dependence of buthionine sulfoximine in reversing resistance to cisplatin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Prognostic factors for outcome of and survival after second-look laparotomy in patients with advanced ovarian carcinoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Telomere association of chromosomes induced by aphidicolin in a normal individual

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

The role of glutathione in drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Gene specific damage and repair after treatment of cells with UV and chemotherapeutical agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Synergistic cytotoxicity of different alkylating agents for epithelial ovarian cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Synergy, additivism and antagonism in immunosuppression. A critical review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=288428

Heterogeneity of antigen expression in benign and malignant breast and ovarian epithelial cells

5 July 2018

1 reference

12 December 2020

Re-treatment of patients with recurrent epithelial ovarian cancer with cisplatin-based chemotherapy

1 reference

12 December 2020

Effects of L-phenylalanine mustard and L-buthionine sulfoximine on murine and human hematopoietic progenitor cells in vitro

1 reference

12 December 2020

Glutathione modulates activation-dependent proliferation of human peripheral blood lymphocyte populations without regulating their activated function

1 reference

12 December 2020

Synergism between aphidicolin and adenoviruses in the induction of breaks at fragile sites on human chromosomes

1 reference

12 December 2020

Screening in ovarian cancer

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Analysis of Michaelis kinetics for two independent, saturable membrane transport functions

1 reference

12 December 2020

A sensitive method to measure physical and chemical carcinogen-induced “unscheduled DNA synthesis” in rapidly dividing eukaryotic cells

1 reference

12 December 2020

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

12 December 2020

Immunotoxins: hybrid molecules of monoclonal antibodies and a toxin subunit specifically kill tumour cells

1 reference

12 December 2020

Inhibition of amino acid transport by cis-diamminedichloroplatinum(II) derivatives in L1210 murine leukemia cells

1 reference

12 December 2020

Interaction of monoclonal antibodies with cell surface antigens of human ovarian carcinomas

1 reference

12 December 2020

Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion

1 reference

12 December 2020

Evaluation of monoclonal antibodies for the development of breast cancer immunotoxins

1 reference

12 December 2020

1 reference

12 December 2020

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines

1 reference

12 December 2020

Phase I and clinical pharmacological evaluation of aphidicolin glycinate

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI116851

1 reference

29 July 2017

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29 July 2017

1 reference