(Q33908733)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21604056%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics (English)

1 reference

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1 February 2020

0 references

17

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1 February 2020

author name string

Wan F Lau

1

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1 February 2020

Jane M Withka

2

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1 February 2020

David Hepworth

3

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1 February 2020

Thomas V Magee

4

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1 February 2020

Yuhua J Du

5

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1 February 2020

Gregory A Bakken

6

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1 February 2020

Michael D Miller

7

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1 February 2020

Zachary S Hendsch

8

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1 February 2020

Venkataraman Thanabal

9

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1 February 2020

Steve A Kolodziej

10

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1 February 2020

Li Xing

11

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1 February 2020

Qiyue Hu

12

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1 February 2020

Lakshmi S Narasimhan

13

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1 February 2020

Robert Love

14

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1 February 2020

Maura E Charlton

15

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1 February 2020

Samantha Hughes

16

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1 February 2020

James E Mills

18

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1 February 2020

publication date

21 May 2011

1 reference

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Journal of Computer - Aided Molecular Design

1 February 2020

published in

1 reference

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1 February 2020

volume

25

1 reference

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1 February 2020

issue

7

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1 February 2020

page(s)

621-636

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Recent developments in fragment-based drug discovery

1 February 2020

cites work

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An integrated approach to fragment-based lead generation: philosophy, strategy and case studies from AstraZeneca's drug discovery programmes.

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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Fragment-based lead discovery: leads by design

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Ligand efficiency: a useful metric for lead selection

21 January 2018

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Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors.

21 January 2018

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Identification of inhibitors of protein kinase B using fragment-based lead discovery

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Library design for NMR-based screening

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Fragment screening by biochemical assay.

21 January 2018

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WaterLOGSY as a method for primary NMR screening: practical aspects and range of applicability.

21 January 2018

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Competition STD NMR for the detection of high-affinity ligands and NMR-based screening

21 January 2018

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Fragment-based lead discovery using X-ray crystallography.

21 January 2018

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The SeeDs approach: integrating fragments into drug discovery

21 January 2018

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A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design

21 January 2018

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Fragment-based screening using X-ray crystallography and NMR spectroscopy

21 January 2018

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Molecular complexity and its impact on the probability of finding leads for drug discovery

21 January 2018

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A ‘Rule of Three’ for fragment-based lead discovery?

21 January 2018

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21 January 2018

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Combinatorial library-based design with Basis Products

21 January 2018

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Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

The Design of Leadlike Combinatorial Libraries

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12 December 2020

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21604056%20AND%20SRC:MED&resulttype=core&format=json

journals/jcamd/LauWHMDBMHTKXHNLCHHM11

1 February 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference