(Q33911220)

30 July 2017

Mitomycin C inhibits ribosomal RNA: a novel cytotoxic mechanism for bioreductive drugs (English)

1 reference

30 July 2017

4

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author name string

Ryan G Snodgrass

series ordinal

1

1 reference

30 July 2017

Abby C Collier

series ordinal

2

1 reference

30 July 2017

Amy E Coon

series ordinal

3

1 reference

30 July 2017

language of work or name

English

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publication date

23 April 2010

1 reference

Journal of Biological Chemistry

30 July 2017

1 reference

30 July 2017

285

1 reference

30 July 2017

25

1 reference

30 July 2017

19068-19075

1 reference

Nucleolus, ribosomes, and cancer

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Bioreductive drugs: from concept to clinic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Decreased xanthine oxidoreductase is a predictor of poor prognosis in early-stage gastric cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Down-regulated xanthine oxidoreductase is a feature of aggressive breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

DT-diaphorase: a target for new anticancer drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Signaling control of mRNA translation in cancer pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Does the ribosome translate cancer?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Structure and function of the eukaryotic ribosome: the next frontier

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

A new mathematical model for relative quantification in real-time RT-PCR

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Mitochondrial genome instability in human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Reductase enzyme expression across the National Cancer Institute Tumor cell line panel: correlation with sensitivity to mitomycin C and EO9.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Reductive activation of mitomycin C by NADH:cytochrome b5 reductase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Adducts of mitomycin C and DNA in EMT6 mouse mammary tumor cells: effects of hypoxia and dicumarol on adduct patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Binding of ethidium derivatives to natural DNA: a 300 MHz 1H NMR study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Decomposition of Ribosomal Particles in Escherichia coli treated with Mitomycin C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Degradation of 28S RNA late in ribosomal RNA maturation in nongrowing lymphocytes and its reversal after growth stimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Regulation of RNA Synthesis in Fibroblasts During Transition from Resting to Growing State

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Regulation of ribosome content in eukaryotes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Synthesis and turnover rates of four rat liver mitochondrial RNA species.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Mitomycin C: mechanism of action, usefulness and limitations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

The effects of three bioreductive drugs (mitomycin C, RSU-1069 and SR4233) on cell lines selected for their sensitivity to mitomycin C or ionising radiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Studies on the mechanism of resistance to mitomycin C and porfiromycin in a human cell strain derived from a cancer-prone individual

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Isolation, identification, and assay of [3H]-porfiromycin adducts of EMT6 mouse mammary tumor cell DNA: effects of hypoxia and dicumarol on adduct patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

MITOMYCINS AND PORFIROMYCIN: CHEMICAL MECHANISM OF ACTIVATION AND CROSS-LINKING OF DNA.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.040477

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.040477

An association between NQO1 genetic polymorphism and risk of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.040477

Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.040477

Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.040477

DNA sequence specificity of mitomycin cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.040477

DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885185

Messenger RNA: Its Origin and Fate in Mammalian Cells

10 December 2018

1 reference

12 December 2020

Relative contributions of mouse liver subcellular fractions to the bioactivation of mitomycin C at various pH levels

1 reference

12 December 2020

RNA as a small-molecule drug target: doubling the value of genomics

1 reference

12 December 2020

Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase

1 reference

12 December 2020

Regulation of the synthesis and the stability of ribosomal RNA during contact inhibition of growth

1 reference

12 December 2020

Bioreductive activation of mitomycin C by DT-diaphorase

1 reference

12 December 2020

Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA

1 reference

12 December 2020

A new cellular target for mitomycin C: a case for mitochondrial DNA

1 reference

12 December 2020

Amplification of (GACA)n simple repeats in an exceptional 14p+ marker chromosome

1 reference

12 December 2020

Enzymology of mitomycin C metabolic activation in tumour tissue. Characterization of a novel mitochondrial reductase

1 reference

12 December 2020

Activity of mitomycin C for aerobic and hypoxic cells in vitro and in vivo

1 reference

12 December 2020

ALTERED DNA ISOLATED FROM CELLS TREATED WITH MITOMYCIN C

1 reference

12 December 2020

Binding of ethidium bromide to ribosomal RNA. Absorption, fluorescence, circular and electric dichroism study

1 reference

12 December 2020

Bioactivation of Mitomycin C by Xanthine Dehydrogenase From EMT6 Mouse Mammary Carcinoma Tumors

1 reference

12 December 2020

The Degradation of Ribosomal RNA in E. coli by Mitomycin C and AF-5, Preferential Inhibitors of DNA Synthesis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.040477

1 reference

30 July 2017

1 reference

30 July 2017

1 reference