(Q33912029)

30 July 2017

1 reference

title

Staurosporine analogues - pharmacological toys or useful antitumour agents? (English)

1 reference

30 July 2017

A Gescher

1

1 reference

30 July 2017

1 May 2000

1 reference

Critical Reviews in Oncology Hematology

30 July 2017

1 reference

30 July 2017

34

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30 July 2017

127-135

1 reference

30 July 2017

2

1 reference

Anticancer drugs acting against signaling pathways

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Protein kinase C isozymes and substrates

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Signaling networks--do all roads lead to the same genes?

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Phorbol esters induce multidrug resistance in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Co-ordinate loss of protein kinase C and multidrug resistance gene expression in revertant MCF-7/Adr breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Antitumor effect of CGP41251, a new selective protein kinase C inhibitor, on human non-small cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN-01, a selective protein kinase C inhibitor.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

The protein kinase C inhibitor CGP 41251, a staurosporine derivative with antitumor activity, reverses multidrug resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Chemosensitization of cancer cells by the staurosporine derivative CGP 41251 in association with decreased P-glycoprotein phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Protein kinase inhibitor-induced alterations of drug uptake, cell cycle and surface antigen expression in human multidrug-resistant (Pgp and MRP) promyelocytic leukemia HL-60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Characterisation of novel human lung carcinoma cell lines selected for resistance to anti-neoplastic analogues of staurosporine

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Structures of staurosporine bound to CDK2 and cAPK--new tools for structure-based design of protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

UCN-01, an anti-tumor drug, is a selective inhibitor of the conventional PKC subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Animal cell cycles and their control

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Differential effects of staurosporine analogues on cell cycle, growth and viability in A549 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

The accumulation of cyclin-dependent kinase inhibitor p27kip1 is a primary response to staurosporine and independent of G1 cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Disposition in mice of 7-hydroxystaurosporine, a protein kinase inhibitor with antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

Effect of intravenous infusions of 12-O-tetradecanoylphorbol-13-acetate (TPA) in patients with myelocytic leukemia: preliminary studies on therapeutic efficacy and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2800%2900058-5

7 January 2021

10.1016/S1040-8428(00)00058-5

Identifiers

DOI

1 reference

release_36hoy5hvlzedhakwunjh2ie7f4

30 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/36hoy5hvlzedhakwunjh2ie7f4

24 November 2022

mapped directly with Wikidata item

PubMed ID

10799837

1 reference

PubMed ID

10799837