(Q33913768)

30 July 2017

title

Evaluation of protein engineering and process optimization approaches to enhance antibody drug manufacturability (English)

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30 July 2017

Greg P Conley

1

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Malini Viswanathan

2

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Ying Hou

3

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Doug L Rank

4

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Allison P Lindberg

5

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Steve M Cramer

6

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Robert C Ladner

7

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Andrew E Nixon

8

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Jie Chen

9

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30 July 2017

publication date

13 June 2011

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Biotechnology and Bioengineering

30 July 2017

published in

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30 July 2017

volume

108

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issue

11

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30 July 2017

page(s)

2634-2644

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Comparison of standard and new generation hydrophobic interaction chromatography resins in the monoclonal antibody purification process.

30 July 2017

cites work

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Characterizing biological products and assessing comparability following manufacturing changes.

21 January 2018

1 reference

Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation

21 January 2018

1 reference

Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library

21 January 2018

1 reference

Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library

21 January 2018

1 reference

Protein aggregation and bioprocessing

21 January 2018

1 reference

Process economics of industrial monoclonal antibody manufacture

21 January 2018

1 reference

Structure-immunogenicity relationships of therapeutic proteins

21 January 2018

1 reference

Quality by design for biopharmaceuticals

21 January 2018

1 reference

Monoclonal antibodies market

21 January 2018

1 reference

Discovery and characterization of a peptide motif that specifically recognizes a non-native conformation of human IgG induced by acidic pH conditions

21 January 2018

1 reference

Solubility as a function of protein structure and solvent components

21 January 2018

1 reference

Downstream processing of monoclonal antibodies--application of platform approaches

21 January 2018

1 reference

Potential aggregation prone regions in biotherapeutics: A survey of commercial monoclonal antibodies.

21 January 2018

1 reference

Exploitation of the adsorptive properties of depth filters for host cell protein removal during monoclonal antibody purification.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIT.23220

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30 July 2017

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