(Q33916129)

30 July 2017

1 reference

title

Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides (English)

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30 July 2017

A M Krieg

1

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PubMed ID

10807001

30 July 2017

language of work or name

English

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publication date

1 December 1999

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30 July 2017

10

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Biochimica et Biophysica Acta

inferred from page(s)

published in

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30 July 2017

1489

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30 July 2017

107-116

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30 July 2017

1

1 reference

A synthetic single-stranded DNA, poly(dG,dC), induces interferon-alpha/beta and -gamma, augments natural killer activity, and suppresses tumor growth

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Oligonucleotide sequences required for natural killer cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Adjuvant effect of polyadenylic.polyuridylic acid on antibody production of recombinant hepatitis B surface antigen in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Efficacy of polyadenylic.polyuridylic acid in the treatment of chronic active hepatitis B.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Polyadenylic-polyuridylic acid enhances the natural cell-mediated cytotoxicity in patients with breast cancer undergoing mastectomy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Immune stimulation by an antisense oligomer complementary to the rev gene of HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Activation of human B cells by phosphorothioate oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

A sense phosphorothioate oligonucleotide directed to the initiation codon of transcription factor NF-kappa B p65 causes sequence-specific immune stimulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Modification of antisense phosphodiester oligodeoxynucleotides by a 5' cholesteryl moiety increases cellular association and improves efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Selection against CpG dinucleotides in lentiviral genes: a possible role of methylation in regulation of viral expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Why is CpG suppressed in the genomes of virtually all small eukaryotic viruses but not in those of large eukaryotic viruses?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Heterogeneity of genomes: measures and values

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Nonspecific Suppression of [3H]Thymidine Incorporation by "Control" Oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Oligodeoxynucleotide modifications determine the magnitude of B cell stimulation by CpG motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Effect of different chemically modified oligodeoxynucleotides on immune stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization, and degradation of DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Mechanism of oligonucleotide uptake by cells: involvement of specific receptors?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Characterization of oligonucleotide transport into living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Lipofection of synthetic oligodeoxyribonucleotide having a palindromic sequence of AACGTT to murine splenocytes enhances interferon production and natural killer activity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Uptake of Oligodeoxyribonucleotides by Lymphoid Cells Is Heterogeneous and Inducible

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Patterns of intracellular compartmentalization, trafficking and acidification of 5'-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Bacterial DNA causes septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG-containing synthetic oligonucleotides promote B and cytotoxic T cell responses to protein antigen: a new class of vaccine adjuvants

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Characterization and modulation of immune stimulation by modified oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Effect of antisense oligonucleotides on cytokine release from human keratinocytes in an in vitro model of skin

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Binding of oligoguanylate to scavenger receptors is required for oligonucleotides to augment NK cell activity and induce IFN.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

Stimulation of in vitro proliferation of murine lymphocytes by synthetic oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4781%2899%2900147-5

7 January 2021

10.1016/S0167-4781(99)00147-5

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10807001