(Q33917505)

English

Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma (English)

1 reference

Europe PubMed Central

30 July 2017

retinal ganglion cell

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Wei Huang

1

1 reference

Europe PubMed Central

30 July 2017

John B Fileta

2

1 reference

Europe PubMed Central

30 July 2017

Adam Dobberfuhl

3

1 reference

Europe PubMed Central

30 July 2017

Theodoros Filippopolous

4

1 reference

Europe PubMed Central

30 July 2017

Yan Guo

5

1 reference

Europe PubMed Central

30 July 2017

Gina Kwon

6

1 reference

Europe PubMed Central

30 July 2017

Cynthia L Grosskreutz

7

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

15 August 2005

1 reference

Europe PubMed Central

30 July 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

30 July 2017

102

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Europe PubMed Central

30 July 2017

34

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Europe PubMed Central

30 July 2017

12242-12247

1 reference

Europe PubMed Central

30 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1186026/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

FK506 blocks activation of the intrinsic caspase cascade after optic nerve crush

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Unbiased estimates of number and size of rat dorsal root ganglion cells in studies of structure and cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Glaucoma: ocular Alzheimer's disease?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

FK506 and its analogs - therapeutic potential for neurological disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

The immunophilin-ligands FK506 and V-10,367 mediate neuroprotection by the heat shock response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Localization of calcineurin in the mature and developing retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

A second calcineurin binding site on the NFAT regulatory domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

The effects of FK506 on retinal ganglion cells after optic nerve crush.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Modeling glaucomatous optic nerve damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

FK506, an immunosuppressant targeting calcineurin function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

FK506 prevents stroke-induced generation of ceramide and apoptosis signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

The coefficient of error of optical fractionator population size estimates: a computer simulation comparing three estimators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

FK506 and the role of immunophilins in nerve regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Number of people with glaucoma worldwide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Reconstitution of active human calcineurin from recombinant subunits expressed in bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

New stereological methods for counting neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Relationship between intraocular pressure and primary open angle glaucoma among white and black Americans. The Baltimore Eye Survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

High brain densities of the immunophilin FKBP colocalized with calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

5 July 2018

Activation of caspase 9 in a rat model of experimental glaucoma

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

TUNEL-positive ganglion cells in human primary open-angle glaucoma.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Caspase-mediated proteolytic activation of calcineurin in thapsigargin-mediated apoptosis in SH-SY5Y neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Effect of glatiramer acetate on primary and secondary degeneration of retinal ganglion cells in the rat.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

The effects of FK506 on neurologic and histopathologic outcome after transient spinal cord ischemia induced by aortic cross-clamping in rats

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

The effects of FK506 on dorsal column axons following spinal cord injury in adult rats: neuroprotection and local regeneration.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

29 October 2018

Localization and characterization of calcineurin in bovine eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

29 October 2018

Calcineurin inhibitors FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

29 October 2018

Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

29 October 2018

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1186026

29 October 2018

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0505138102

21 January 2018

Protective effect of FK506 in the reperfusion model after short-term occlusion of middle cerebral artery in the rat: assessment by autoradiography using [125I]PK-11195

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noninvasive measurement of rat intraocular pressure with the Tono-Pen

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death of retinal ganglion cells during experimental glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rat model of chronic pressure-induced optic nerve damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of intraocular pressure elevation after aqueous humor outflow obstruction in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glaucoma drops control intraocular pressure and protect optic nerves in a rat model of glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and ocular histopathological findings in a patient with normal-pressure glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunophilin ligand FK506, but not GPI-1046, protects against neuronal death and inhibits c-Jun expression in the substantia nigra pars compacta following transection of the rat medial forebrain bundle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16103353

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0505138102

1 reference

Europe PubMed Central

30 July 2017

2005PNAS..10212242H

0 references

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

ResearchGate publication ID

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