(Q33919198)

30 July 2017

title

Drotrecogin alfa (activated) may attenuate severe sepsis-associated encephalopathy in clinical septic shock (English)

1 reference

sepsis-associated encephalopathy

30 July 2017

0 references

1 reference

1 reference

1 reference

Herbert Spapen

1

1 reference

30 July 2017

Duc Nam Nguyen

2

1 reference

30 July 2017

Joris Troubleyn

3

1 reference

30 July 2017

Luc Huyghens

4

1 reference

30 July 2017

Johan Schiettecatte

5

1 reference

30 July 2017

publication date

7 April 2010

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30 July 2017

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30 July 2017

volume

14

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30 July 2017

issue

2

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30 July 2017

page(s)

R54

1 reference

https://scigraph.springernature.com/pub.10.1186/cc8947

30 July 2017

exact match

0 references

cites work

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1 reference

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Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells

28 July 2018

1 reference

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Recombinant human activated protein C: current insights into its mechanism of action

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Drug Insight: steroids in CNS infectious diseases--new indications for an old therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Activated protein C and sepsis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Sepsis-associated encephalopathy: a magnetic resonance imaging and spectroscopy study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Septic encephalopathy: relationship to serum and cerebrospinal fluid levels of adhesion molecules, lipid peroxides and S-100B protein

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Sepsis associated encephalopathy studied by MRI and cerebral spinal fluid S100B measurement.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Intensive insulin therapy after severe traumatic brain injury: a randomized clinical trial

29 October 2018

1 reference

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Treatment of hyperglycemia in ischemic stroke (THIS): a randomized pilot trial

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Elevated S100B levels do not correlate with the severity of encephalopathy during sepsis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Activated protein C reduces endotoxin-induced white matter injury in the developing rat brain

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Brain lesions in septic shock: a magnetic resonance imaging study.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Elevated serum levels of S-100beta protein and neuron-specific enolase are associated with brain injury in patients with severe sepsis and septic shock.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

The neuropathology of septic shock.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Apoptosis of neurons in cardiovascular autonomic centres triggered by inducible nitric oxide synthase after death from septic shock

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Impaired subcortical and cortical sensory evoked potential pathways in septic patients.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Efficacy and safety of recombinant human activated protein C for severe sepsis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

The spectrum of septic encephalopathy. Definitions, etiologies, and mortalities.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2887172

Predictive value of S-100beta and neuron-specific enolase serum levels for adverse neurologic outcome after cardiac surgery

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20374626

12 December 2020

inferred from PubMed ID database lookup

Release of glial tissue-specific proteins after acute stroke: A comparative analysis of serum concentrations of protein S-100B and glial fibrillary acidic protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20374626

12 December 2020

inferred from PubMed ID database lookup

Detrimental effects of high-dose methylprednisolone sodium succinate on serum concentrations of hepatic and renal function indicators in severe sepsis and septic shock. The Methylprednisolone Severe Sepsis Study Group

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20374626

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/CC8947

1 reference

release_xrsze73kyzbajjv2abwe2kyhu4

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xrsze73kyzbajjv2abwe2kyhu4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2887172

1 reference

30 July 2017

1 reference