(Q33922947)

30 July 2017

1 reference

title

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications (English)

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30 July 2017

1 reference

molecular interaction

1 reference

Bourguet W

1

1 reference

PubMed ID

11050318

30 July 2017

Germain P

series ordinal

2

1 reference

PubMed ID

11050318

30 July 2017

Gronemeyer H

series ordinal

3

1 reference

30 July 2017

1 October 2000

1 reference

Trends in Pharmacological Sciences

30 July 2017

1 reference

30 July 2017

21

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30 July 2017

381-388

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30 July 2017

10

1 reference

Nuclear receptor coregulators: cellular and molecular biology

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Increasing the complexity of coactivation in nuclear receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

A canonical structure for the ligand-binding domain of nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Structure and specificity of nuclear receptor-coactivator interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Molecular basis of agonism and antagonism in the oestrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

The RXR heterodimers and orphan receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Terminal differentiation of human breast cancer through PPAR gamma.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Peroxisome proliferator-activated receptors: nuclear control of metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Nuclear receptor regulation of cholesterol and bile acid metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Conformational adaptation of agonists to the human nuclear receptor RAR gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Cloning of a novel receptor expressed in rat prostate and ovary

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Two distinct actions of retinoid-receptor ligands

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Transcriptional cross-talk, the second mode of steroid hormone receptor action.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Therapeutic potential of selective modulators of nuclear receptor action

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Nuclear receptor cofactors as chromatin remodelers

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Mechanism of corepressor binding and release from nuclear hormone receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Molecular determinants of nuclear receptor-corepressor interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

20-Epi analogues of 1,25-dihydroxyvitamin D3 are highly potent inducers of DRIP coactivator complex binding to the vitamin D3 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

A structural role for hormone in the thyroid hormone receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Atomic structure of progesterone complexed with its receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

Structural aspects of agonism and antagonism in the oestrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901548-0

7 January 2021

10.1016/S0165-6147(00)01548-0

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11050318