(Q33923773)

30 July 2017

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title

Matrix metalloproteinases in remodeling of the normal and neoplastic mammary gland (English)

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30 July 2017

Rudolph-Owen LA

1

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PubMed ID

10819526

30 July 2017

Matrisian LM

series ordinal

2

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30 July 2017

1 April 1998

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Journal of Mammary Gland Biology and Neoplasia

30 July 2017

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30 July 2017

3

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30 July 2017

2

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30 July 2017

177-189

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https://scigraph.springernature.com/pub.10.1023/a:1018746923474

30 July 2017

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cites work

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Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas

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Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties

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Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth.

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The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse

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Matrix metalloproteinase matrilysin is constitutively expressed in adult human exocrine epithelium

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Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression

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Expression of activated gelatinase in human invasive breast carcinoma

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Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture

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Matrix metalloproteinases are expressed during ductal and alveolar mammary morphogenesis, and misregulation of stromelysin-1 in transgenic mice induces unscheduled alveolar development

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Expression of stromelysin-3 and nm23 in breast carcinoma and related tissues

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Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene

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Induction of membrane-type matrix metalloproteinase 1 (MT1-MMP) expression in human fibroblasts by breast adenocarcinoma cells

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Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix.

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Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology.

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A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts

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Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium

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Overexpression of the matrix metalloproteinase matrilysin results in premature mammary gland differentiation and male infertility

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Involvement of extracellular matrix constituents in breast cancer

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Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

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Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2

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12 December 2020

Type IV collagenases in invasive tumors

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12 December 2020

Activation of progelatinase A and progelatinase A/TIMP-2 complex by membrane type 2-matrix metalloproteinase

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12 December 2020

Expression of stromelysin-1 and TIMP-1 in the involuting mammary gland and in early invasive tumors of the mouse.

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A matrix metalloproteinase expressed on the surface of invasive tumour cells

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Negative regulation in correct tissue-specific expression of mouse mammary tumor virus in transgenic mice

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The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis.

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Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution

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Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4.

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Quantitation of milk proteins and their mRNAs in rat mammary gland at various stages of gestation and lactation

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Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions

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The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family

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The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis

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Rapid onset of apoptosis in vitro follows disruption of beta 1-integrin/matrix interactions in human colonic crypt cells.

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Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4

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Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland

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Synthesis of gelatinases by rat mammary epithelial and myoepithelial cell lines

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Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis.

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Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence

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Correlation between stromelysin-3 mRNA level and outcome of human breast cancer

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Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice

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Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.

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A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

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Proteolytic remodeling of extracellular matrix

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Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

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12 December 2020

Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94)

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12 December 2020

Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction

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12 December 2020

Disruption of epithelial cell-matrix interactions induces apoptosis

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12 December 2020

MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.

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12 December 2020

Protoneoplasia: The Molecular Biology of Murine Mammary Hyperplasia

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12 December 2020

Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity

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Changing views of the role of matrix metalloproteinases in metastasis

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12 December 2020

Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas

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12 December 2020

Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis

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12 December 2020

The mammary gland: a unique organ for the study of development and tumorigenesis

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12 December 2020

Stromelysin-3 expression promotes tumor take in nude mice

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12 December 2020

Enhanced synthesis of gelatinase and stromelysin by myoepithelial cells during involution of the rat mammary gland

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12 December 2020

72 KD and 92 KD type IV collagenase, type IV collagen, and laminin mRNAs in breast cancer: a study by in situ hybridization

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12 December 2020

Stromelysin-3 expression in breast cancer biopsies: clinico-pathological correlations

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12 December 2020

Stromelysin-3 in stromal tissue as a control factor in breast cancer behavior

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12 December 2020

Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression

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12 December 2020

Implication of collagen type I-induced membrane-type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma

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12 December 2020

Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.

1 reference

12 December 2020

Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue

1 reference

12 December 2020

The spatial and temporal expression of the alpha 2 beta 1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis

1 reference

12 December 2020

Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1018746923474

1 reference

PubMed ID

10819526

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

10819526