(Q33924084)

30 July 2017

1 reference

title

Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters (English)

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30 July 2017

Kazanietz MG

1

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30 July 2017

publication date

1 May 2000

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30 July 2017

published in

Molecular Carcinogenesis

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30 July 2017

volume

28

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30 July 2017

issue

1

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30 July 2017

page(s)

5-11

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Complexities of the protein kinase C pathway

30 July 2017

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1 reference

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Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain

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Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death.

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Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element

21 January 2018

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Phorbol ester inhibits the phosphorylation of the retinoblastoma protein without suppressing cyclin D-associated kinase in vascular smooth muscle cells

21 January 2018

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Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells

21 January 2018

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Regulation of the cell cycle at the G2/M boundary in metastatic melanoma cells by 12-O-tetradecanoyl phorbol-13-acetate (TPA) by blocking p34cdc2 kinase activity

21 January 2018

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Tumor promotion by depleting cells of protein kinase C delta

21 January 2018

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Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence

21 January 2018

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Residues in the second cysteine-rich region of protein kinase C delta relevant to phorbol ester binding as revealed by site-directed mutagenesis

21 January 2018

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Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

21 January 2018

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21 January 2018

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Identification of a major protein kinase C-binding protein and substrate in rat embryo fibroblasts. Decreased expression in transformed cells

21 January 2018

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21 January 2018

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21 January 2018

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Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

21 January 2018

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Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells

21 January 2018

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beta2-chimaerin is a novel target for diacylglycerol: binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain

21 January 2018

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Bcr encodes a GTPase-activating protein for p21rac

21 January 2018

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

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Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

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21 January 2018

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Effectors for the Rho GTPases

21 January 2018

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A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

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21 January 2018

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Expression of alpha 1-chimaerin (rac-1 GAP) alters the cytoskeletal and adhesive properties of fibroblasts

21 January 2018

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The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

21 January 2018

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Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery

21 January 2018

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Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins

21 January 2018

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Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo

21 January 2018

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Human munc13 is a diacylglycerol receptor that induces apoptosis and may contribute to renal cell injury in hyperglycemia

21 January 2018

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21 January 2018

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Protein kinase Cdelta is activated by caspase-dependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes

21 January 2018

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Phorbol ester TPA rapidly prevents activation of p34cdc2 histone H1 kinase and concomitantly the transition from G2 phase to mitosis in synchronized HeLa cells

21 January 2018

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10.1002/(SICI)1098-2744(200005)28:1<5::AID-MC2>3.0.CO;2-G

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference