(Q33924373)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Toward classification of BRCA1 missense variants using a biophysical approach (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Laura Itzhaki

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Pamela J E Rowling

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

8 April 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

30 January 2020

number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

20080-20087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

BRCT domains: phosphopeptide binding and signaling modules

30 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

The ubiquitin E3 ligase activity of BRCA1 and its biological functions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Network modeling links breast cancer susceptibility and centrosome dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Founder mutations in BRCA1 and BRCA2 genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Functional impact of missense variants in BRCA1 predicted by supervised learning

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Cellular functions of the BRCA tumour-suppressor proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Insights into the molecular basis of human hereditary breast cancer from studies of the BRCA1 BRCT domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Substrates of the BRCA1-dependent ubiquitin ligase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Loss of protein structure stability as a major causative factor in monogenic disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

I-Mutant2.0: predicting stability changes upon mutation from the protein sequence or structure

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Functional characterization of BRCA1 sequence variants using a yeast small colony phenotype assay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Cytoplasmic mislocalization of BRCA1 caused by cancer-associated mutations in the BRCT domain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

SIFT: Predicting amino acid changes that affect protein function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Human non-synonymous SNPs: server and survey

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Predicting changes in the stability of proteins and protein complexes: a study of more than 1000 mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

SNPs, protein structure, and disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Functional analysis of BRCA1 C-terminal missense mutations identified in breast and ovarian cancer families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Calculation of protein extinction coefficients from amino acid sequence data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2888420

Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

Eris: an automated estimator of protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

Characterisation of the BRCT Domains of the Breast Cancer Susceptibility Gene Product BRCA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

Stability scale and atomic solvation parameters extracted from 1023 mutation experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.088922

Characterization of Common BRCA1 and BRCA2 Variants

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20378548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Folding intermediates of wild-type and mutants of barnase. I. Use of phi-value analysis and m-values to probe the cooperative nature of the folding pre-equilibrium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20378548

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.088922

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20378548%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

20378548

1 reference