(Q33926185)

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Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Autumn Ruiz

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

M Sarah Hill

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Kimberly Schmitt

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

John Guatelli

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Edward B Stephens

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

0 references

publication date

24 June 2008

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

378

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

58-68

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

1 reference

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Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

1 reference

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1 reference

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Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C HIV-1 clinical isolate

1 reference

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1 reference

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Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.

1 reference

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5 July 2018

A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein

1 reference

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Global and regional distribution of HIV-1 genetic subtypes and recombinants in 2004.

1 reference

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The effect of the membrane-proximal tyrosine-based sorting signal of HIV-1 gp41 on viral infectivity depends on sequences within gp120.

1 reference

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Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques

1 reference

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The replicative fitness of primary human immunodeficiency virus type 1 (HIV-1) group M, HIV-1 group O, and HIV-2 isolates

1 reference

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Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques.

1 reference

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Characterization of a novel vpu-harboring simian immunodeficiency virus from a Dent's Mona monkey (Cercopithecus mona denti).

1 reference

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5 July 2018

Identification of a region within the cytoplasmic domain of the subtype B Vpu protein of human immunodeficiency virus type 1 (HIV-1) that is responsible for retention in the golgi complex and its absence in the Vpu protein from a subtype C HIV-1.

1 reference

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5 July 2018

Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIV(cpz) strains

1 reference

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5 July 2018

Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes

1 reference

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5 July 2018

HIV-1 Nef disrupts MHC-I trafficking by recruiting AP-1 to the MHC-I cytoplasmic tail

1 reference

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5 July 2018

Vpu: a multifunctional protein that enhances the pathogenesis of human immunodeficiency virus type 1.

1 reference

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Potential new anti-human immunodeficiency virus type 1 compounds depress virus replication in cultured human macrophages

1 reference

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Identification of a new simian immunodeficiency virus lineage with a vpu gene present among different cercopithecus monkeys (C. mona, C. cephus, and C. nictitans) from Cameroon

1 reference

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Characterization of a novel simian immunodeficiency virus (SIVmonNG1) genome sequence from a mona monkey (Cercopithecus mona).

1 reference

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

1 reference

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Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.

1 reference

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5 July 2018

HIV-1 Nef stabilizes the association of adaptor protein complexes with membranes

1 reference

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Characterization of a novel simian immunodeficiency virus with a vpu gene from greater spot-nosed monkeys (Cercopithecus nictitans) provides new insights into simian/human immunodeficiency virus phylogeny

1 reference

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Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tailed macaques

1 reference

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A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells.

1 reference

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Comparison of Vpu sequences from diverse geographical isolates of HIV type 1 identifies the presence of highly variable domains, additional invariant amino acids, and a signature sequence motif common to subtype C isolates

1 reference

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A molecular clone of simian-human immunodeficiency virus (DeltavpuSHIV(KU-1bMC33)) with a truncated, non-membrane-bound vpu results in rapid CD4(+) T cell loss and neuro-AIDS in pig-tailed macaques

1 reference

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Structural and functional analysis of the membrane-spanning domain of the human immunodeficiency virus type 1 Vpu protein

1 reference

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A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

1 reference

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A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

1 reference

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Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

1 reference

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1 reference

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1 reference

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1 reference

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The Vpu protein of human immunodeficiency virus type 1 forms cation-selective ion channels

1 reference

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

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The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains.

1 reference

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1 reference

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The human immunodeficiency virus type 1 encoded Vpu protein is phosphorylated by casein kinase-2 (CK-2) at positions Ser52 and Ser56 within a predicted alpha-helix-turn-alpha-helix-motif

1 reference

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1 reference

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1 reference

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Identification of a protein encoded by the vpu gene of HIV-1.

1 reference

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1 reference

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Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes

1 reference

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Molecular epidemiology of HIV: tracking AIDS pandemic

1 reference

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1 reference

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Amiloride derivatives block ion channel activity and enhancement of virus-like particle budding caused by HIV-1 protein Vpu.

1 reference

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1 reference

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Ion channels formed by HIV-1 Vpu: a modelling and simulation study

1 reference

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Rapid degradation of CD4 in cells expressing human immunodeficiency virus type 1 Env and Vpu is blocked by proteasome inhibitors

1 reference

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29 October 2018

Identification of an ion channel activity of the Vpu transmembrane domain and its involvement in the regulation of virus release from HIV-1-infected cells

1 reference

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Is HIV-1 evolving to a less virulent form in humans?

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.05.022

7 January 2021

Phosphorylation of both phosphoacceptor sites in the HIV-1 Vpu cytoplasmic domain is essential for Vpu-mediated ER degradation of CD4

1 reference

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7 January 2021

Identifiers

10.1016/J.VIROL.2008.05.022

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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